ArticlePsychophysiology2023
Cerebellar EEG source localization reveals age-related compensatory activity moderated by genetic risk for Alzheimer's disease.
Article in Psychophysiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Functional and effective EEG connectivity patterns in Alzheimer's disease and mild cognitive impairment: a systematic review.Frontiers in aging neuroscience · 2025Pooled it
- Cerebellar Electrical Activity as a Marker for Predicting Brain Health and Disease: A Review.Brain sciences · 2026Review
- Investigating Cerebello-Cortical Networks With EEG: Advances and Future Challenges.Cerebellum (London, England) · 2026Review
- Associations between incremental exercise capacity and multimodal brain characteristics across training levels.Frontiers in human neuroscience · 2026Article
- Cerebellar White Matter Microstructure Is Associated With Age, Cerebrospinal Fluid Amyloid Beta Levels, and Cognition in Cognitively Unimpaired Older Adults.Human brain mapping · 2025Article
- Alzheimer's disease cerebrospinal fluid biomarker levels and APOE genetic status are associated with hippocampal-cerebellar functional connectivity.Neurobiology of aging · 2025Article
- Toward a more comprehensive understanding of network centrality disruption in amnestic mild cognitive impairment: a MEG multilayer approach.Alzheimer's research & therapy · 2024Article
- Age-related neural changes underlying long-term recognition of musical sequences.Communications biology · 2024Article
- Cerebellum in Alzheimer's disease and other neurodegenerative diseases: an emerging research frontier.MedComm · 2024Review
- PEARL-Neuro Database: EEG, fMRI, health and lifestyle data of middle-aged people at risk of dementia.Scientific data · 2024Article
- Editorial: Insights in neurocognitive aging and behavior: 2022.Frontiers in aging neuroscience · 2024Article
- Genetic Risk for Alzheimer's Disease Alters Perceived Executive Dysfunction in Cognitively Healthy Middle-Aged and Older Adults.Journal of Alzheimer's disease reports · 2024Article
- The influence of cerebellum on visual selective attention in patients with multiple lacunar cerebral infarction and its neuromodulatory mechanisms.Frontiers in human neuroscience · 2024Article
- Cerebellum's Contribution to Attention, Executive Functions and Timing: Psychophysiological Evidence from Event-Related Potentials.Brain sciences · 2023Review
Corrections and comments
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2 authors.
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Abstract
The apolipoprotein-E (APOE) ε4 allele is the greatest genetic risk factor for late-onset Alzheimer's disease (AD), but alone it is not sufficiently predictive. Because neuropathological changes associated with AD begin decades before cognitive symptoms, neuroimaging of healthy, cognitively intact ε4 carriers (ε4+) may enable early characterization of patterns associated with risk for future decline. Research in the cerebral cortex highlights a period of compensatory recruitment in elders and ε4+, which serves to maintain cognitive functioning. Yet, AD-related changes may occur even earlier in the cerebellum. Advances in electroencephalography (EEG) source localization now allow effective modeling of cerebellar activity. Importantly, healthy aging and AD are associated with declines in both cerebellar functions and executive functioning (EF). However, it is not known whether cerebellar activity can detect pre-symptomatic AD risk. Thus, the current study analyzed cerebellar EEG source localization during an EF-dependent stop-signal task (i.e., inhibitory control) in healthy, intact older adults (M
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