Evidence map›Paper›PMID 37492805›Full record

ArticleCureus2023

Common Side Effects of Pfizer COVID-19 Vaccine: An Experience From Pakistan.

Syed Muhammad Safi Haider, Shaf Ali Alvi, Hamza Khan, Rameen Majeed, Tatheer Syed, Adnan Anwar, Atif A Hashmi

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Syed Muhammad Safi HaiderInternal Medicine, Hamdard College of Medicine and Dentistry, Karachi, PAK.
Shaf Ali AlviInternal Medicine, Hamdard College of Medicine and Dentistry, Karachi, PAK.
Hamza KhanGeneral Surgery, Hamdard College of Medicine and Dentistry, Karachi, PAK.
Rameen MajeedBiochemistry, Jinnah Sindh Medical University, Karachi, PAK.
Tatheer SyedPublic Health, Jinnah Sindh Medical University, Karachi, PAK.
Adnan AnwarPhysiology, Hamdard College of Medicine and Dentistry, Karachi, PAK.
Atif A HashmiPathology, Liaquat National Hospital and Medical College, Karachi, PAK.
Liaquat National Hospital · PKCivil Hospital Karachi · PKJinnah Sindh Medical University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) epidemic spread quickly. Vaccines are now being distributed to stop the infectious spread and halt fatalities. The Pfizer-BioNTech vaccine was the first mRNA-based vaccine introduced to boost immunity against COVID-19; however, it could lead to various adverse reactions. Therefore, the aim of this study was to assess the prevalence of Pfizer vaccine side effects among participants. Methods This was a multicenter cross-sectional study that was performed using a non-probability sampling method. The study period was about six months from March 1, 2022, to August 31, 2022. A total of 1000 participants who received two doses of the Pfizer vaccine met the inclusion criteria. Demographic details of participants, for example, gender, age, comorbidities, Pfizer vaccine with both doses along with booster dose, previous exposure to coronavirus disease 2019 (COVID-19) infection, and the incidence of any local and systemic side effects following the first and second doses of vaccine, were reported.  Results The study findings showed that out of 1000 participants, 644 (64.4%) were males and 356 (35.6%) were females; their mean age was 43.06±14.98 years. Among them, 280 (28.0%) had hypertension and 356 (35.6%) had diabetes. Following the first dose of the Pfizer vaccine, burning at the injection site and fever were the most commonly reported side effects in 704 (70.4%) and 700 (70.0%) participants, respectively. Following the second dose of the Pfizer vaccine, muscle pain was the most commonly reported side effect in 628 (62.8%) participants. Conclusion This study concluded that the most frequent adverse effects of the Pfizer vaccine were burning at the injection site, fever, pain at the injection site, muscle pain, swelling at the injection site, and joint pain. Moreover, the first dose was associated with more side effects than the second dose.

Indexed as

burningcovid-19feverjoint painpainpfizer vaccineside effectsswellingvaccine

Identifiers

PMID37492805
PMCPMC10363686
OpenAlexW4381997243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.