Evidence map›Paper›PMID 37492745›Full record

ArticleGenes & diseases2023

Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways.

Colemonts-Vroninks Haaike, Norman P Brendan, Van Laere Sven, Davison S Andrew, Marcélis Lionel, Casimir Georges, Goyens Philippe, Claes Paul, De Bundel Dimitri, Martens Geert and 4 more

Abstract read
In one paragraph

Article in Genes & diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Colemonts-Vroninks HaaikeVrije Universiteit Brussel, Liver Therapy & Evolution Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.
Norman P BrendanUniversity of Liverpool, Dept. of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Liverpool L7 8TX, United Kingdom.
Van Laere SvenVrije Universiteit Brussel, Interfaculty Center Data Processing and Statistics, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.
Davison S AndrewUniversity of Liverpool, Dept. of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Liverpool L7 8TX, United Kingdom.
Marcélis LionelUniversité Libre de Bruxelles, Laboratoire de Pédiatrie, Brussels B-1050, Belgium.
Casimir GeorgesUniversité Libre de Bruxelles, Laboratoire de Pédiatrie, Brussels B-1050, Belgium.
Goyens PhilippeUniversité Libre de Bruxelles, Laboratoire de Pédiatrie, Brussels B-1050, Belgium.
Claes PaulVrije Universiteit Brussel, In Vitro Liver Disease Modelling Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.
De Bundel DimitriVrije Universiteit Brussel, Experimental Pharmacology (EFAR) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.
Martens GeertAZ Delta General Hospital, Department of Laboratory Medicine, Roeselare 8800, Belgium.
Ranganath Lakshminarayan RaoLiverpool University Hospitals NHS Foundation Trust, Clinical Biochemistry and Metabolic Medicine, Liverpool L3 5PS, United Kingdom.
Vanhaecke TamaraVrije Universiteit Brussel, In Vitro Liver Disease Modelling Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.
Gallagher James AUniversity of Liverpool, Dept. of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Liverpool L7 8TX, United Kingdom.
De Kock JoeryVrije Universiteit Brussel, Liver Therapy & Evolution Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103, Brussels B-1090, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37492745
PMCPMC10363636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.