Evidence map›Paper›PMID 37492509›Full record

ReviewRSC advances2023

Curcumin-loaded mesoporous silica nanoparticles for drug delivery: synthesis, biological assays and therapeutic potential - a review.

Milad Iranshahy, Mohammad Yahya Hanafi-Bojd, Seyed Hadi Aghili, Mehrdad Iranshahi, Seyed Mohammad Nabavi, Satar Saberi, Rosanna Filosa, Iman Farzam Nezhad, Maede Hasanpour

Open access · goldAbstract readReview
In one paragraph

Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Freeze-Dried CS/PVP/PVA Composite Scaffolds Doped with Curcumin and SiOInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Milad IranshahyDepartment of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences Mashhad Iran.
Mohammad Yahya Hanafi-BojdNanomedicine Department, Faculty of Medicine, Birjand University of Medical Sciences Birjand Iran.
Seyed Hadi AghiliValiasr Hospital, Department of Neurosurgery Tehran Iran.
Mehrdad IranshahiBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences Mashhad Iran Hasanpourmm3@mums.ac.ir maede.hasanpour@yahoo.com.
Seyed Mohammad NabaviAdvanced Medical Pharma (AMP-Biotec), Biopharmaceutical Innovation Centre Via Cortenocera 82030 San Salvatore Telesino BN Italy.ORCID https://orcid.org/0000-0001-8859-5675
Satar SaberiDepartment of Chemistry, Faculty of Science, Farhangian University Tehran Iran.
Rosanna FilosaDipartimento di Scienze e Tecnologie, Università Degli Studi Del Sannio Benevento Italy.
Iman Farzam NezhadDepartment of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad Mashhad Iran.
Maede HasanpourBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences Mashhad Iran Hasanpourmm3@mums.ac.ir maede.hasanpour@yahoo.com.ORCID https://orcid.org/0000-0002-8260-6123
Mashhad University of Medical Sciences · IRBirjand University of Medical Sciences · IRFarhangian University · IRFerdowsi University of Mashhad · IRUniversity of Sannio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin-loaded mesoporous silica nanoparticles (MSNs) have shown promise as drug delivery systems to address the limited pharmacokinetic characteristics of curcumin. Functionalization with folic acid and PEGylation enhance anticancer activity, biocompatibility, stability, and permeability. Co-delivery with other drugs results in synergistically enhanced cytotoxic activity. Environment-responsive MSNs prevent undesirable drug leakage and increase selectivity towards target tissues. This review summarizes the methods of Cur-loaded MSN synthesis and functionalization and their application in various diseases, and also highlights the potential of Cur-loaded MSNs as a promising drug delivery system.

Identifiers

PMID37492509
PMCPMC10363773
OpenAlexW4385226199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.