Evidence map›Paper›PMID 37492382›Full record

ArticleFrontiers in radiology2023

Deep learning-based left ventricular segmentation demonstrates improved performance on respiratory motion-resolved whole-heart reconstructions.

Yitong Yang, Zahraw Shah, Athira J Jacob, Jackson Hair, Teodora Chitiboi, Tiziano Passerini, Jerome Yerly, Lorenzo Di Sopra, Davide Piccini, Zahra Hosseini and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Automatic vessel segmentation and reformation of non-contrast coronary magnetic resonance angiography using transfer learning-based three-dimensional U-net with attention mechanism.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Yitong YangWallace H. Coulter Department of Biomedical Engineering, Emory University and the Georgia Institute of Technology, Atlanta, GA, United States.
Zahraw ShahWallace H. Coulter Department of Biomedical Engineering, Emory University and the Georgia Institute of Technology, Atlanta, GA, United States.
Athira J JacobDigital Technology and Innovation, Siemens Medical Solutions USA, Princeton, NJ, United States.
Jackson HairWallace H. Coulter Department of Biomedical Engineering, Emory University and the Georgia Institute of Technology, Atlanta, GA, United States.
Teodora ChitiboiDigital Technology and Innovation, Siemens Medical Solutions USA, Princeton, NJ, United States.
Tiziano PasseriniDigital Technology and Innovation, Siemens Medical Solutions USA, Princeton, NJ, United States.
Jerome YerlyDiagnostic and Interventional Radiology, Lausanne University Hospital, Lausanne, Switzerland.
Lorenzo Di SopraDiagnostic and Interventional Radiology, Lausanne University Hospital, Lausanne, Switzerland.
Davide PicciniAdvanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Switzerland.
Zahra HosseiniMR R&D Collaboration, Siemens Medical Solutions USA, Atlanta, GA, United States.
Puneet SharmaDigital Technology and Innovation, Siemens Medical Solutions USA, Princeton, NJ, United States.
Anurag SahuMR R&D Collaboration, Siemens Medical Solutions USA, Atlanta, GA, United States.
Matthias StuberDiagnostic and Interventional Radiology, Lausanne University Hospital, Lausanne, Switzerland.
John N OshinskiWallace H. Coulter Department of Biomedical Engineering, Emory University and the Georgia Institute of Technology, Atlanta, GA, United States.
Siemens (United States) · USUniversity of Lausanne · CHGeorgia Institute of Technology · USSiemens Healthcare (United States) · USThe Wallace H. Coulter Department of Biomedical Engineering · USSiemens (Switzerland) · CH

Funding

Coronary Fractional Flow Reserve Determined Using MRI and CFDR01EB027774 · NIBIB · EMORY UNIVERSITY · PI OSHINSKI, JOHN N · 2020 to 2025
$1.7M
NIBIB NIH HHS R01 EB027774
6 · The paper itself

Abstract

Introduction: Deep learning (DL)-based segmentation has gained popularity for routine cardiac magnetic resonance (CMR) image analysis and in particular, delineation of left ventricular (LV) borders for LV volume determination. Free-breathing, self-navigated, whole-heart CMR exams provide high-resolution, isotropic coverage of the heart for assessment of cardiac anatomy including LV volume. The combination of whole-heart free-breathing CMR and DL-based LV segmentation has the potential to streamline the acquisition and analysis of clinical CMR exams. The purpose of this study was to compare the performance of a DL-based automatic LV segmentation network trained primarily on computed tomography (CT) images in two whole-heart CMR reconstruction methods: (1) an in-line respiratory motion-corrected (Mcorr) reconstruction and (2) an off-line, compressed sensing-based, multi-volume respiratory motion-resolved (Mres) reconstruction. Given that Mres images were shown to have greater image quality in previous studies than Mcorr images, we Method: This retrospective study used 15 patients who underwent clinically indicated 1.5 T CMR exams with a prototype ECG-gated 3D radial phyllotaxis balanced steady state free precession (bSSFP) sequence. For each reconstruction method, the absolute volume difference (AVD) of the automatically and manually segmented LV volumes was used as the primary quantity to investigate whether 3D DL-based LV segmentation generalized better on Mcorr or Mres 3D whole-heart images. Additionally, we assessed the 3D Dice similarity coefficient between the manual and automatic LV masks of each reconstructed 3D whole-heart image and the sharpness of the LV myocardium-blood pool interface. A two-tail paired Student's Results & Discussion: The AVD in the respiratory Mres reconstruction was lower than the AVD in the respiratory Mcorr reconstruction: 7.73 ± 6.54 ml vs. 20.0 ± 22.4 ml, respectively ( Conclusion: We conclude that the DL-based 3D automatic LV segmentation network trained on CT images and fine-tuned on MR images generalized better on Mres images than on Mcorr images for quantifying LV volumes.

Indexed as

deep learning 3D segmentationfree-breathingLV volumemotion compensationwhole-heart CMR

Identifiers

PMID37492382
PMCPMC10365088
OpenAlexW4379231763

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.