Evidence map›Paper›PMID 37492219›Full record

ReviewResearch and reports in tropical medicine2023

Field-Deployable Treatments For Leishmaniasis: Intrinsic Challenges, Recent Developments and Next Steps.

Thalia Pacheco-Fernandez, Hannah Markle, Chaitenya Verma, Ryan Huston, Sreenivas Gannavaram, Hira L Nakhasi, Abhay R Satoskar

Open access · goldAbstract readReview
In one paragraph

Review in Research and reports in tropical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Antileishmanial Activity ofMolecules (Basel, Switzerland) · 2026
    Article
  5. Veterinary research forum : an international quarterly journal · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. 3-styrylcoumarin scaffold-based derivatives as a new approach for leishmaniasis intervention: biological and molecular modeling studies.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  11. Eugenol-Rich Essential Oil fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Thalia Pacheco-Fernandez *Division of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research Food and Drug Administration, Silver Spring, MD, 20993, USA.ORCID 0000-0003-2741-0942
Hannah Markle *Division of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research Food and Drug Administration, Silver Spring, MD, 20993, USA.
Chaitenya VermaDepartment of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH, 43201, USA.
Ryan HustonDepartment of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH, 43201, USA.ORCID 0000-0003-1884-1695
Sreenivas GannavaramDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research Food and Drug Administration, Silver Spring, MD, 20993, USA.
Hira L NakhasiDivision of Emerging and Transfusion Transmitted Disease, Center for Biologics Evaluation and Research Food and Drug Administration, Silver Spring, MD, 20993, USA.
Abhay R SatoskarDepartment of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH, 43201, USA.
Center for Biologics Evaluation and Research · USThe Ohio State University Wexner Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmaniasis is a neglected tropical disease endemic primarily to low- and middle-income countries, for which there has been inadequate development of affordable, safe, and efficacious therapies. Clinical manifestations of leishmaniasis range from self-healing skin lesions to lethal visceral infection with chances of relapse. Although treatments are available, secondary effects limit their use outside the clinic and negatively impact the quality of life of patients in endemic areas. Other non-medicinal treatments, such as thermotherapies, are limited to use in patients with cutaneous leishmaniasis but not with visceral infection. Recent studies shed light to mechanisms through which

Indexed as

ferroptosisfield-deployable therapieshematopoietic stem cellsleishmaniasismonocytesrepurposing drugs

Identifiers

PMID37492219
PMCPMC10364832
OpenAlexW4384817517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.