ArticleSaudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
Bowman's membrane lenticule tuck-in: A new approach for the management of neurotrophic ulcers.
Article in Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Acellular Bowman Layer and Descemet Membrane Allografts for Non-Ectatic Anterior Corneal Diseases: A Narrative Review of Emerging Evidence.Ophthalmology and therapy · 2026Review
- Novel Surgical Approach for Limbal Dermoid Excision: Utilizing Bowman's Membrane Lenticule and Autologous Limbal Stem Cell Transplantation for Enhanced Epithelial Healing and Visual Outcomes.Vision (Basel, Switzerland) · 2025Article
- Delayed onset Aspergillus niger keratitis post-DALK associated with bandage contact lens: a case report highlighting the importance of vigilant postoperative care and management.GMS ophthalmology cases · 2025Article
- Intrastromal autologous buffy coat as an adjuvant therapy for fungal corneal ulcer: a case report of two cases.Romanian journal of ophthalmologyArticle
- Pediatric cystinosis: Corneal cystine deposits and papilledema in a 4-year-old: A case report.Medicine internationalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate a new surgical method for managing nonhealing neurotrophic ulcers using a novel technique of tucking-in Bowman's membrane lenticule in the ulcer defect.
methodsA total of 22 eyes of 22 patients with neurotrophic ulcers of various etiologies and stages were included and underwent a surgical process where a donor Bowman's membrane lenticule was harvested and fashioned according to the lesion and tucked inside the ulcer after making a recess in anterior one-third of stroma all around 360 degrees. The primary outcomes measured were healing (stable epithelialization at 12 months) and best-corrected visual acuity (BCVA) improvement.
resultsTwenty-two eyes of 22 patients with neurotrophic ulcers underwent Bowman's membrane lenticule tuck-in procedure. Complete re-epithelialization was achieved in 21 eyes (95.45%). The average healing time was 2.77 ± 0.79 weeks. The mean corneal thickness improved from 267.36 ± 94.56 mm preoperatively to 435.9 ± 47.71 mm at six months postoperatively. The mean BCVA also improved from 0.05 ± 0.07 preoperatively to 0.24 ± 0.24 postoperatively one year. One patient (4.54%) showed recurrence after one month, and the epithelial defect persisted till the end of the study.
conclusionDonor Bowman's membrane lenticule tuck-in for neurotrophic ulcers is a safe and highly effective treatment and requires minimal instruments and expertise.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.