ArticleJournal of public health (Oxford, England)2023
Trends in cause-specific mortality: deaths of despair in Spain, 1980-2019.
Article in Journal of public health (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Longer residence in disadvantaged neighborhoods predicts both a syndrome of despair and deaths of despair: Complementary evidence from nationwide register and birth-cohort studies.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- The decline of 'Deaths of Despair' in Italy: unveiling this phenomenon in a new context.Population health metrics · 2026Article
- Deaths of despair in England, 2014-2022: trends by sex and socioeconomic deprivation before and after COVID-19.International journal of public health · 2026Article
- Deaths of despair before and during the COVID-19 pandemic: a comparative analysis of 27 European countries and the United States.Frontiers in public health · 2026Article
- Educational inequalities in deaths of despair in 14 OECD countries: a cross-sectional observational study.Journal of epidemiology and community health · 2025Observational
- "They're Lacking Purpose. It's a Recipe for Suicide.": Masculinity and Gender-Based Inequalities in Deaths of Despair in England.American journal of men's healthArticle
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Authors and funding
5 authors.
Funding
Abstract
backgroundResearch from various countries has shown increases in alcohol- and drug-related deaths and suicide, known as 'deaths of despair' over recent decades, particularly among low-educated middle-aged individuals. However, little is known about trends in death-of-despair causes in Spain. Therefore, we aim to descriptively examine this among 25-64-year-olds from 1980 to 2019 and by educational attainment for the years 2017-19.
methodsWe obtained mortality and population data from the National Institute of Statistics to estimate age-standardized mortality rates and assess educational inequalities using the relative index of inequality (RII).
resultsDeaths of despair as a share of total mortality slightly increased from 2000 onwards, particularly among 25-64-year-old men (from 9 to 10%). Only alcohol-related mortality declined relatively more since 1980 compared with all-cause mortality. Regarding educational differences, low-educated men presented higher mortality rates in all death-of-despair causes (alcohol-related: RII 3.54 (95% CI: 2.21-5.66); drug-related: RII 3.49 (95% CI: 1.80-6.77); suicide: RII 1.97 (95% CI: 1.49-2.61)). Women noteworthy differences were only observed for alcohol-related (RII 3.50 (95% CI: 2.13-5.75)).
conclusionsFindings suggest an increasing proportion of deaths of despair among 25-64-year-olds since 2000, particularly among men. Public health policies are needed to reduce and prevent these premature and preventable causes of mortality.
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