Evidence map›Paper›PMID 37491319›Full record

ArticleRNA (New York, N.Y.)2023

In vivo structure probing of RNA in

Allison M Williams, Elizabeth A Jolley, Michel Geovanni Santiago-Martínez, Cheong Xin Chan, Robin R Gutell, James G Ferry, Philip C Bevilacqua

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. In Vivo RNA Chemical Footprinting Analysis in Archaea.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Allison M WilliamsDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-9886-9163
Elizabeth A JolleyCenter for RNA Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0003-3107-5403
Michel Geovanni Santiago-MartínezDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-9872-7894
Cheong Xin ChanAustralian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane QLD 4072, Australia.ORCID 0000-0002-3729-8176
Robin R GutellDepartment of Integrative Biology, The University of Texas at Austin, Austin, Texas 78712, USA.ORCID 0000-0002-5919-0801
James G FerryDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Philip C BevilacquaDepartment of Biochemistry and Molecular Biology, Pennsylvania State University, University Park, Pennsylvania 16802, USA pcb5@psu.edu.ORCID 0000-0001-8074-3434
Pennsylvania State University · USThe University of Queensland · AUThe University of Texas at Austin · US

Funding

RNA folding and catalysis at the interface of biophysics and genomicsR35GM127064 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PHILIP C BEVILACQUA · 2018 to 2026
$3.4M
NIGMS NIH HHS R35 GM127064
6 · The paper itself

Abstract

Structure probing combined with next-generation sequencing (NGS) has provided novel insights into RNA structure-function relationships. To date, such studies have focused largely on bacteria and eukaryotes, with little attention given to the third domain of life, archaea. Furthermore, functional RNAs have not been extensively studied in archaea, leaving open questions about RNA structure and function within this domain of life. With archaeal species being diverse and having many similarities to both bacteria and eukaryotes, the archaea domain has the potential to be an evolutionary bridge. In this study, we introduce a method for probing RNA structure in vivo in the archaea domain of life. We investigated the structure of ribosomal RNA (rRNA) from

Indexed as

ArchaeaRNABacteriaMethanolMethanosarcinaRibosomesMethanolRNAArchaeaRNA probingrRNAStructure-seq

Identifiers

PMID37491319
PMCPMC10578495
OpenAlexW4385259489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.