Evidence map›Paper›PMID 37491130›Full record

ArticleBMJ open respiratory research2023

Right ventricular functional recovery assessment with stress echocardiography and cardiopulmonary exercise testing after pulmonary embolism: a pilot prospective multicentre study.

Chinthaka Bhagya Samaranayake, John Upham, Khoa Tran, Luke S Howard, Sean Nguyen, Myo Lwin, James Anderson, Sudhir Wahi, Laura C Price, Stephen Wort and 3 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Chinthaka Bhagya SamaranayakeNational Pulmonary Hypertension Service, Royal Brompton Hospital, London, UK c.samaranayake@uq.net.au.ORCID 0000-0003-3996-4205
John UphamFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-0017-3433
Khoa TranFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Luke S HowardNational Pulmonary Hypertension Service, Hammersmith Hospital, London, UK.
Sean NguyenPrincess Alexandra Hospital, Woolloongabba, Queensland, Australia.
Myo LwinNational Pulmonary Hypertension Service, Royal Brompton Hospital, London, UK.
James AndersonSunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.
Sudhir WahiFaculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Laura C PriceNational Pulmonary Hypertension Service, Royal Brompton Hospital, London, UK.ORCID 0000-0001-5250-660X
Stephen WortNational Pulmonary Hypertension Service, Royal Brompton Hospital, London, UK.
Wei LiNational Pulmonary Hypertension Service, Royal Brompton Hospital, London, UK.
Colm McCabe *National Pulmonary Hypertension Service, Royal Brompton Hospital, London, UK.
Gregory J Keir *Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Royal Brompton Hospital · GBThe University of Queensland · AUHammersmith Hospital · GBPrincess Alexandra Hospital · AUSunshine Coast University Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundData on right ventricular (RV) exercise adaptation following acute intermediate and high-risk pulmonary embolism (PE) remain limited. This study aimed to evaluate the symptom burden, RV functional recovery during exercise and cardiopulmonary exercise parameters in survivors of intermediate and high-risk acute PE.

methodsWe prospectively recruited patients following acute intermediate and high-risk PE at four sites in Australia and UK. Study assessments included stress echocardiography, cardiopulmonary exercise testing (CPET) and ventilation-perfusion (VQ) scan at 3 months follow-up.

resultsThirty patients were recruited and 24 (median age: 55 years, IQR: 22) completed follow-up. Reduced peak oxygen consumption (VO

conclusionIn our cohort, impaired RV adaptation on exercise was seen in almost one-third of patients. Combined stress echocardiography and CPET may enable more accurate phenotyping of patients with persistent symptoms following acute PE to allow timely detection of long-term complications.

Indexed as

Echocardiography, StressPulmonary EmbolismExercise TestHumansMiddle AgedOxygenProspective StudiesQuality of LifeOxygenexerciseimaging/CT MRI etcprimary pulmonary hypertensionpulmonary embolism

Identifiers

PMID37491130
PMCPMC10373684
OpenAlexW4385249229

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.