ArticleInternal medicine journal2023
Associations between symptoms and functional capacity in patients after COVID-19 infection and community controls.
Article in Internal medicine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- A mixed-methods study comparing clinical and patient-reported perspectives on long COVID: insights from electronic health records and narrative journal entries.BMC infectious diseases · 2026Observational
- Presentation and temporal nature of postacute sequelae of SARS-CoV-2 infection in a US national cohort.Brain, behavior, & immunity - health · 2026Article
- Observational
- Physical Function Differences by COVID-19 Status: A Cross-sectional Analysis From the RECOVER Adult Cohort.Physical therapy · 2025Observational
- Maximal oxygen uptake, pulmonary function and walking economy are not impaired in patients diagnosed with long COVID.European journal of applied physiology · 2025Article
- Physical exercise-related manifestations of long COVID: A systematic review and meta-analysis.Journal of exercise science and fitness · 2024Review
- Evaluating performance on the Glittre-ADL test in men with long COVID 3 years after a SARS-CoV-2 infection.Journal of exercise science and fitness · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundPost-acute sequelae of COVID-19 (PASC or 'long COVID') reflect ongoing symptoms, but these are non-specific and common in the wider community. Few reports of PASC have been compared with a control group.
aimsTo compare symptoms and objective impairment of functional capacity in patients with previous COVID-19 infection with uninfected community controls.
methodsIn this community-based, cross-sectional study of functional capacity, 562 patients from Western Melbourne who had recovered from COVID-19 infections in 2021 and 2022 were compared with controls from the same community and tested for functional capacity pre-COVID-19. Functional impairment (<85% of the predicted response) was assessed using the Duke Activity Status Index (DASI) and 6-min walk distance (6MWD) test. A subgroup underwent cardiopulmonary exercise testing before and after exercise training.
resultsOf 562 respondents (age 54 ± 12 years, 69% women), 389 were symptomatic. Functional impairment (<85% predicted metabolic equivalent of tasks) was documented by DASI in 149 participants (27%), and abnormal 6MWD (<85% predicted) was observed in 14% of the symptomatic participants. Despite fewer risk factors and younger age, patients with COVID-19 had lower functional capacity by 6MWD (P < 0.001) and more depression (P < 0.001) than controls. In a pilot group of seven participants (age 58 ± 12 years, two women, VO
conclusionsAlthough most participants (69%) had symptoms consistent with long COVID, significant subjective functional impairment was documented in 27% and objective functional impairment in 14%. An exercise training programme might be beneficial for appropriately selected patients.
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