Evidence map›Paper›PMID 37490451›Full record

ArticlePloS one2023

Patterns of testing in the extensive Danish national SARS-CoV-2 test set-up.

Mie Agermose Gram, Nina Steenhard, Arieh Sierra Cohen, Anne-Marie Vangsted, Kåre Mølbak, Thøger Gorm Jensen, Christian Holm Hansen, Steen Ethelberg

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mie Agermose GramDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen S, Denmark.ORCID 0000-0001-7908-0039
Nina SteenhardTestCentre Denmark, Statens Serum Institut, Copenhagen S, Denmark.
Arieh Sierra CohenTestCentre Denmark, Statens Serum Institut, Copenhagen S, Denmark.
Anne-Marie VangstedTestCentre Denmark, Statens Serum Institut, Copenhagen S, Denmark.
Kåre MølbakDivision of Infectious Disease Preparedness, Statens Serum Institut, Copenhagen S, Denmark.
Thøger Gorm JensenDepartment of Clinical Microbiology, Odense University Hospital Odense C, Odense, Denmark.
Christian Holm HansenDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen S, Denmark.
Steen EthelbergDepartment of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen S, Denmark.ORCID 0000-0002-9709-356X
Statens Serum Institut · DKUniversity of Southern Denmark · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Danish national SARS-CoV-2 mass test system was among the most ambitious worldwide. We describe its set-up and analyse differences in patterns of testing per demography and time period in relation to the three waves of SARS-CoV-2 transmission in Denmark.

methodsWe included all reported PCR- and rapid antigen-tests performed between 27 February 2020 and 10 March 2022 among all residents aged 2 years or above. Descriptive statistics and Poisson regression models were used to analyse characteristics of individuals tested for SARS-CoV-2 using a national cohort study design.

resultsA total of 63.7 million PCR-tests and 60.0 million rapid antigen-tests were performed in the study period, testing 90.9% and 78.8% of the Danish population at least once by PCR or antigen, respectively. Female sex, younger age, Danish heritage and living in the capital area were all factors positively associated with the frequency of PCR-testing. The association between COVID-19 vaccination and PCR-testing changed from negative to positive over time.

conclusionWe provide details of the widely available, free-of-charge, national SARS-CoV-2 test system, which served to identify infected individuals, assist isolation of infectious individuals and contact tracing, and thereby mitigating the spread of SARS-CoV-2 in the Danish population. The test system was utilized by nearly the entire population at least once, and widely accepted across different demographic groups. However, demographic differences in the test uptake did exist and should be considered in order not to cause biases in studies related to SARS-CoV-2, e.g., studies of transmission and vaccine effectiveness.

Indexed as

COVID-19Cohort StudiesCOVID-19 VaccinesDenmarkFemaleHumansSARS-CoV-2COVID-19 Vaccines

Identifiers

PMID37490451
PMCPMC10368237
OpenAlexW4385237188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.