Evidence map›Paper›PMID 37490230›Full record

ArticleMikrochimica acta2023

Electrochemical nano-biosensor based on electrospun indium zinc oxide nanofibers for the determination of complement component 3 protein.

Dinesh Ramkrushna Rotake, Tanmoya Nemai Ghosh, Shiv Govind Singh

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dinesh Ramkrushna Rotake *Department of Electrical Engineering, Indian Institute of Technology Hyderabad, Hyderabad, Telangana, 502285, India.
Tanmoya Nemai Ghosh *Department of Electrical Engineering, Indian Institute of Technology Hyderabad, Hyderabad, Telangana, 502285, India.
Shiv Govind SinghDepartment of Electrical Engineering, Indian Institute of Technology Hyderabad, Hyderabad, Telangana, 502285, India. sgsingh@ee.iith.ac.in.ORCID http://orcid.org/0000-0001-7319-879X
Indian Institute of Technology Hyderabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a progressive chronic neurodegenerative retinal disease leading to vision loss, irreversible blindness, and visual impairment in older adults worldwide. Complement component 3 (C3) protein has been identified as the most predominant biomarker towards early diagnosis of AMD; therefore, there is an utmost requirement for non-invasive detection of C3 protein in the tear fluids of AMD patients. Considering this, we report an insightful electrochemical sensor capable of detecting clinically relevant concentrations ranging from 10 fg/mL to 1 μg/mL using electrospun indium-doped zinc oxide (InZnO) nanofibers as the transducing layer. The InZnO nanofibers have facilitated high anti-C3 antibody loading of 3.42 × 10

Indexed as

NanofibersZinc OxideAgedComplement C3HumansIndiumZincComplement C3Indiumindium oxideZincZinc OxideComplement component C3Electrochemical sensorsModified glassy carbon electrodeNanofibers (NFs)SAM (self-assembled monolayer)VoltammetryWHO (World Health Organization)

Identifiers

PMID37490230
OpenAlexW4385230454

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.