Observational studyEuropean journal of epidemiology2023
Incidence, prevalence and mortality of chronic liver diseases in Sweden between 2005 and 2019.
Observational study in European journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Health-related quality of life in patients with liver cirrhosis following adjunctive nurse-based care versus standard medical care: a pragmatic, multicentre, randomised controlled study.BMJ open gastroenterology · 2025Trial
- MASLD, diabetes and PMOS across the female life stages.Diabetologia · 2026Review
- Enhanced liver fibrosis score is associated with cognitive performance during an 11-year follow-up period.Hepatology communications · 2026Article
- A Unified Histopathological Framework of Liver Fibrogenesis in Chronic Viral Hepatitis B, C and Coinfection.Diseases (Basel, Switzerland) · 2026Article
- Large Language Models for Diagnosis and Prognosis of Chronic Liver Diseases: A Systematic Review.Health science reports · 2026Review
- Excess mortality from cirrhosis by neighbourhood deprivation, aetiology, and clinical presentation: a Swedish register-based cohort study.EClinicalMedicine · 2026Article
- From Birth to Midlife-Liver Function, Fibrosis and Mortality in Individuals with Severe Alpha-1-Antitrypsin Deficiency Identified by Neonatal Screening.Journal of clinical medicine · 2026Article
- Liver-pancreas communication in disease and drug development.Acta pharmaceutica Sinica. B · 2026Review
- Characteristics and Clinical Outcomes in Patients With Cirrhosis due to MASLD in Sweden.Liver international : official journal of the International Association for the Study of the Liver · 2026Article
- Aspects of implementing a nurse-based follow-up of patients with liver cirrhosis: A qualitative study.PloS one · 2026Article
- Decline in Complications and Mortality in Chronic Liver Disease and Cirrhosis: A Population-Based Cohort Study From Northeastern Italy.United European gastroenterology journal · 2025Article
- Alcohol Consumption Behaviors and Liver Disease: Is There a Safer Drinking Practices?Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Adverse pregnancy and birth outcomes in women with biopsy-proven MASLD: a nationwide cohort study.EClinicalMedicine · 2025Article
- Cirrhosis epidemiology in Denmark 1998-2022, and 2030 forecast.JHEP reports : innovation in hepatology · 2025Article
- Observational
- Timely Follow-Up After a First Diagnosis of Cirrhosis is Associated With Reduced Mortality but No Impact on Rehospitalisations: A Population-Based Cohort of 8852 Patients.Alimentary pharmacology & therapeutics · 2025Article
- Past, current, and future trends in the prevalence of primary sclerosing cholangitis and inflammatory bowel disease across England (2015-2027): a nationwide, population-based study.The Lancet regional health. Europe · 2024Article
- Article
- Patient perceived quality of cirrhosis care- adjunctive nurse-based care versus standard medical care: a pragmatic multicentre randomised controlled study.BMC nursing · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUpdated data on the incidence, prevalence, and regional differences of chronic liver disease are missing from many countries. In this study, we aimed to describe time trends, incidence, prevalence, and mortality of a wide range of chronic liver diseases in Sweden.
methodsIn this register-based, nationwide observational study, patients with a register-based diagnosis of chronic liver disease, during 2005-2019, were retrieved from the Swedish National Board of Health and Welfare. Annual age-standardized incidence and mortality rates, and prevalence per 100,000 inhabitants was calculated and stratified on age, sex, and geographical region.
resultsThe incidence of alcohol-related cirrhosis increased by 47% (2.6% annually), reaching an incidence rate of 13.1/100,000 inhabitants. The incidence rate of non-alcoholic fatty liver disease and unspecified liver cirrhosis increased by 217% and 87% (8.0 and 4.3% annually), respectively, reaching an incidence rate of 15.2 and 18.7/100,000 inhabitants, and a prevalence of 24.7 and 44.8/100,000 inhabitants. Furthermore, incidence rates of chronic hepatitis C declined steeply, but liver malignancies have become more common. The most common causes of liver-related mortality were alcohol-related liver disease and unspecified liver disease.
conclusionThe incidence rates of diagnosed non-alcoholic fatty liver disease, alcohol-related cirrhosis, unspecified liver cirrhosis, and liver malignancies have increased during the last 15 years. Worryingly, mortality in several liver diseases increased, likely reflecting increasing incidences of cirrhosis in spite of a decreasing rate of hepatitis C. Significant disparities exist across sex and geographical regions, which need to be considered when allocating healthcare resources.
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