Evidence map›Paper›PMID 37490125›Full record

ArticleMolecular diversity2024

Design, synthesis, molecular docking, and dynamic studies of novel thiazole derivatives incorporating benzimidazole moiety and assessment as antibacterial agents.

Raju Chedupaka, Amrutha V Audipudi, Akanksha Ashok Sangolkar, Srikanth Mamidala, Papisetti Venkatesham, Santhosh Penta, Rajeswar Rao Vedula

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular diversity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Raju ChedupakaDepartment of Chemistry, National Institute of Technology, Warangal, Telangana, 506004, India.
Amrutha V AudipudiDepartment of Botany and Microbiology, Acharya Nagarjuna University, Guntur, A.P., 522510, India.
Akanksha Ashok SangolkarDepartment of Chemistry, National Institute of Technology, Warangal, Telangana, 506004, India.
Srikanth MamidalaDepartment of Chemistry, National Institute of Technology, Warangal, Telangana, 506004, India.
Papisetti VenkateshamDepartment of Chemistry, National Institute of Technology, Warangal, Telangana, 506004, India.
Santhosh PentaDepartment of Chemistry, National Institute of Technology, Warangal, Telangana, 506004, India.
Rajeswar Rao VedulaDepartment of Chemistry, National Institute of Technology, Warangal, Telangana, 506004, India. rajeswarnitw@gmail.com.
National Institute of Technology Warangal · INAcharya Nagarjuna University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A general and sustainable approach for the synthesis of benzimidazole-thiazole compounds via an efficient, one-pot, domino, pseudo-four-component reaction using 5-amino-2-mercaptobenzimidazole, aralkyl halides, ammonium thiocyanate, and substituted α-bromo-acetophenones in glacial acetic acid at ambient temperature to give final compounds (4a-p) in good yields in shorter time. The spectral data of synthesized compounds were evaluated by analytical and spectral techniques (IR,

Indexed as

Anti-Bacterial AgentsBenzimidazolesDrug DesignMicrobial Sensitivity TestsMolecular Docking SimulationThiazolesMolecular Dynamics SimulationStreptococcus pneumoniaeStructure-Activity RelationshipAnti-Bacterial AgentsbenzimidazoleBenzimidazolesThiazoles5-Amino-2-mercaptobenzimidazoleAntibacterial activityComputational studiesMCR approachThiazole

Identifiers

PMID37490125
OpenAlexW4385230057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.