Evidence map›Paper›PMID 37489837›Full record

SynthesisCancer2023

Social isolation and social connectedness among young adult cancer survivors: A systematic review.

Rina S Fox, Grace E Armstrong, Julia S Gaumond, Taylor F D Vigoureux, Corinne H Miller, Stacy D Sanford, John M Salsman, Emmanuel Katsanis, Terry A Badger, Damon R Reed and 5 more

Abstract readSystematic Review
In one paragraph

Synthesis in Cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. The association among psychological factors, pain severity and quality of life in people living beyond adolescent and young adult cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Pooled it
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  5. Article
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  8. Differences in quality of life between early onset colorectal cancer patients compared to older patients: a qualitative study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  9. Article
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  12. Life beyond remission: physical, emotional, and social reintegration of cancer survivors in Tunisia-a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  15. Review
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  19. Interdependence, marginalisation, and self-acceptance: lived experiences of cancer patients in rural China.International journal of qualitative studies on health and well-being · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rina S FoxUniversity of Arizona College of Nursing, Tucson, Arizona, USA.ORCID 0000-0003-4307-5259
Grace E ArmstrongNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Julia S GaumondNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Taylor F D VigoureuxUniversity of North Florida, Jacksonville, Florida, USA.
Corinne H MillerNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Stacy D SanfordNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
John M SalsmanWake Forest School of Medicine, Winston-Salem, North Carolina, USA.ORCID 0000-0003-2317-4006
Emmanuel KatsanisUniversity of Arizona Cancer Center, Tucson, Arizona, USA.
Terry A BadgerUniversity of Arizona College of Nursing, Tucson, Arizona, USA.ORCID 0000-0002-2403-9562
Damon R ReedMoffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0002-8238-2465
Brian D GonzalezMoffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0001-5108-5735
Heather S L JimMoffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0001-7353-3711
Echo L WarnerUniversity of Utah College of Nursing, Salt Lake City, Utah, USA.ORCID 0000-0002-5998-9744
David E VictorsonNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-3530-8633
Laura B OswaldMoffitt Cancer Center, Tampa, Florida, USA.ORCID 0000-0001-6281-2512

Funding

Improving sleep in gynecologic cancer survivorsK08CA247973 · NCI · UNIVERSITY OF ARIZONA · PI FOX, RINA S · 2021 to 2025
$926k
NCI NIH HHS K08 CA247973NCI NIH HHS K08CA247973
6 · The paper itself

Abstract

backgroundSocial isolation and connectedness are social determinants of health that have demonstrated effects on cancer-related outcomes. These constructs have been systematically evaluated among pediatric and older adult cancer populations. In this review, the authors evaluated the prevalence, correlates, and psychosocial implications of social isolation and connectedness among young adult (YA) cancer survivors aged 18-39 years.

methodsPeer-reviewed articles published in English before June 2021 were identified from database searches and included articles' reference lists according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Included articles described studies that assessed social isolation and/or connectedness among YA cancer survivors.

resultsIn total, 5094 unique records were identified; 4143 were excluded after title/abstract screening, and 907 were excluded after full-text review. Forty-four articles were included. Few studies used validated measures or directly assessed social isolation or connectedness. Social isolation was similarly prevalent among YAs and older cancer survivors and noncancer populations. Demographic, clinical, and behavioral risk and protective factors for social isolation were identified. Social isolation was related to worse psychological well-being, whereas social connectedness was often, but not always, related to better psychological well-being.

conclusionsThis growing literature underscores the relevance of social isolation and connectedness as important health determinants among YA cancer survivors. The identified risk and protective factors can identify YAs who especially may benefit from screening for social isolation. Future studies are needed that directly, reliably, and validly evaluate social isolation and connectedness to inform the development of interventions to decrease isolation and increase connectedness.

Indexed as

Cancer SurvivorsNeoplasmsAgedChildHumansSocial IsolationYoung Adultcancer survivorshipsocial connectednesssocial isolationsystematic reviewyoung adults

Identifiers

PMID37489837
PMCPMC10584376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.