Evidence map›Paper›PMID 37489619›Full record

ArticlePhysics in medicine and biology2023

Ionization detail parameters and cluster dose: a mathematical model for selection of nanodosimetric quantities for use in treatment planning in charged particle radiotherapy.

Bruce Faddegon, Eleanor A Blakely, Lucas Burigo, Yair Censor, Ivana Dokic, Naoki Domínguez Kondo, Ramon Ortiz, José Ramos Méndez, Antoni Rucinski, Keith Schubert and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Physics in medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Bruce FaddegonUniversity of California San Francisco, Department of Radiation Oncology 1600 Divisadero Street, San Francisco, CA 94143 United States of America.ORCID 0000-0002-4573-1582
Eleanor A BlakelyLoma Linda University School of Medicine, 11175 Campus St, Loma Linda, CA 92350, United States of America.ORCID 0000-0003-4779-7021
Lucas BurigoDivision of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-8053-9414
Yair CensorDepartment of Mathematics, University of Haifa, 199 Aba Khoushy Ave. Mount Carmel, Haifa, 3498838, Israel.ORCID 0000-0003-2247-818X
Ivana DokicClinical Cooperation Unit Translational Radiation Oncology, German Cancer Consortium (DKTK) Core-Center Heidelberg, National Center for Tumor Diseases (NCT), Heidelberg University Hospital (UKHD) and German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Naoki Domínguez KondoUniversity of California San Francisco, Department of Radiation Oncology 1600 Divisadero Street, San Francisco, CA 94143 United States of America.ORCID 0000-0002-4410-1925
Ramon OrtizUniversity of California San Francisco, Department of Radiation Oncology 1600 Divisadero Street, San Francisco, CA 94143 United States of America.ORCID 0000-0002-4628-8121
José Ramos MéndezUniversity of California San Francisco, Department of Radiation Oncology 1600 Divisadero Street, San Francisco, CA 94143 United States of America.ORCID 0000-0002-8106-5142
Antoni RucinskiInstitute of Nuclear Physics Polish Academy of Sciences, Radzikowskiego 152, 31-342 Kraków, Poland.ORCID 0000-0002-5815-4606
Keith SchubertBaylor University, 1311 S 5th St, Waco, TX 76706, United States of America.ORCID 0000-0003-2718-5087
Niklas WahlDivision of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.ORCID 0000-0002-1451-223X
Reinhard SchulteLoma Linda University School of Medicine, 11085 Campus St, Loma Linda, CA 92350, United States of America.ORCID 0000-0002-7892-2756
University of California, San Francisco · USGerman Cancer Research Center · DEBaylor University · USCarmel (Israel) · ILInstitute of Nuclear Physics, Polish Academy of Sciences · PLLawrence Berkeley National Laboratory · USLoma Linda University · US

Funding

Ionization Detail - Biologically based treatment planning for particle therapy beyond LET-RBER01CA266467 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BRUCE FADDEGON, Jian-Hua Mao · 2022 to 2026
$3.0M
NAPTA: Optimizing clinical trial design & delivery of particle therapy for cancerP20CA183640 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BLAKELY, ELEANOR A, ROACH, MACK · 2015 to 2016
$997k
NCI NIH HHS P20 CA183640NCI NIH HHS R01 CA266467
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Radiation OncologyCell LineModels, BiologicalProtonsRelative Biological EffectivenessProtonsnanodosimetryparticle therapyRBEtrack structure simulationtreatment planning

Identifiers

PMID37489619
PMCPMC10565507
OpenAlexW4385230214

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.