Evidence map›Paper›PMID 37489602›Full record

Trial reportAmerican journal of Alzheimer's disease and other dementias

A Study on the Effect of Traditional Chinese Exercise Combined With Rhythm Training on the Intervention of Older Adults With Mild Cognitive Impairment.

Qiang Zhang, Menglong Zhu, Lili Huang, Miao Zhu, Xiaolei Liu, Ping Zhou, Tao Meng

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of Alzheimer's disease and other dementias. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiang ZhangGraduate School, Capital University of Physical Education and Sports, Beijing, China.ORCID 0000-0002-1556-3493
Menglong ZhuEncephalopathy Center, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Beijing, China.
Lili HuangChinese Wushu Academy, Beijing Sport University, Beijing, China.
Miao ZhuGraduate School, Capital University of Physical Education and Sports, Beijing, China.
Xiaolei LiuChinese Traditional Regimen Exercise Intervention Research Center, Beijing Sport University, Beijing, China.
Ping ZhouSchool of Art, Beijing Sport University, Beijing, China.
Tao MengSchool of Wushu and Performance, Capital University of Physical Education and Sports, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo examine the effect of combination exercise program on cognitive function of older adults with mild cognitive impairment (MCI), and identify biomarkers associated with improvement of cognitive functions.

methodsSubjects were 42 older adults (ages, 60-80 years) with MCI. The subjects were randomly classified to traditional Chinese exercise combined with rhythm training group (TCE + RTG, n = 14), walking group (WG, n = 14), and control group (CG, n = 14), according to their level of MMSE scores. These groups exercised for 60 minutes at 1 session, 3 sessions a week for 12 weeks. The intervention program was conducted under multitask conditions to stimulate attention and memory, and the control group attended 3 education classes. Measurements were administered before, after the 6-week, and after the 12-week intervention period; Measurements: The Mini-mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Symbol Digit Modalities Test (SDMT), Activities of Daily Living Scale (ADL), and the 17-item Hamilton Depression Scale (HAMD-17), along with the brain-derived neurotrophic factor (BDNF). A repeated-measures analysis of variance was used to examine differences among the 3 groups and between the 3 testing times (pre-test vs middle-test vs post-test).

results(1) The TCE + RTG showed significant improvement in the MMSE, MoCA, SDMT, and ADL scale test results (

conclusionThe results suggested that a TCE + RT is beneficial for improving memory and maintaining general cognitive function and peripheral blood BDNF levels in older adults with MCI. Peripheral blood BDNF levels may predict improvement of cognitive functions in older adults with MCI. Further studies are required to determine the positive effects of TCE + RT on cognitive function in older adults with MCI. Trial Registration: ChiCTR2200058545, Registered 10 April 2022.

Indexed as

Cognitive DysfunctionExerciseActivities of Daily LivingAgedAged, 80 and overBrain-Derived Neurotrophic FactorCognitionEast Asian PeopleHumansMiddle AgedBrain-Derived Neurotrophic Factorcognitive functioncognitive impairmentolder adultsrhythm trainingtraditional Chinese exercise

Identifiers

PMID37489602
PMCPMC10624104

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.