Evidence map›Paper›PMID 37489327›Full record

ArticleVision (Basel, Switzerland)2023

Repeatability and Comparability of Retinal Blood Vessel Caliber Measurements by OCTA.

Joby Tsai, Samuel Asanad, Martha Whiting, Xuemin Zhang, Laurence Magder, Osamah Saeedi

Abstract read
In one paragraph

Article in Vision (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Association and Multimodal Model of Retinal Mid-Peripheral Capillary Free Zones with Structural and Functional Parameters in Diabetic Patients Without Clinical Retinopathy.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  3. DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2026
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joby TsaiDepartment of Ophthalmology, Broward Health, Deerfield Beach, FL 33064, USA.ORCID 0000-0003-1155-049X
Samuel AsanadDepartment of Ophthalmology and Visual Sciences, University of Maryland, Baltimore, MD 21201, USA.
Martha WhitingDepartment of Ophthalmology and Visual Sciences, University of Maryland, Baltimore, MD 21201, USA.
Xuemin ZhangDepartment of Ophthalmology and Visual Sciences, University of Maryland, Baltimore, MD 21201, USA.
Laurence MagderDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Osamah SaeediDepartment of Ophthalmology and Visual Sciences, University of Maryland, Baltimore, MD 21201, USA.ORCID 0000-0002-3082-4604

Funding

Direct Measures of Retinal Blood Flow and Autoregulation as Robust Biomarkers for Early GlaucomaR01EY031731 · NEI · UNIVERSITY OF MARYLAND BALTIMORE · PI SAEEDI, OSAMAH JAWAID · 2021 to 2025
$1.6M
NEI NIH HHS R01 EY031731
6 · The paper itself

Abstract

backgroundTo investigate the repeatability in vessel caliber measurements by optical coherence tomography angiography (OCTA).

methodsIn this prospective study, 28 patients (47 eyes) underwent sequential OCTA imaging of the optic nerve head and macula. Two independent masked graders measured vessel caliber for sequential images of the optic nerve head and macula. The average vessel width was determined and variability between graders and images.

resultsA total of 8400 measurements of 420 vessels from 84 OCTA images were included in the analysis. Overall, inter-grader agreement was excellent (ICC 0.90). The coefficient of variation (CoV) for all repeated OCTA images was 0.10. Greater glaucoma severity, older age, macular location, and diagnosis of diabetes were associated with thinner vessels (

conclusionsOverall, the repeatability of vessel caliber measurements by OCTA was high and variability low. There was greater variability in the measurement of macular vessels, possibly due to technical limitations in acquiring accurate vessel widths for smaller macular vessels.

Indexed as

optical coherence tomography angiography (OCTA)primary open-angle glaucoma (POAG)repeatabilityvessel caliber

Identifiers

PMID37489327
PMCPMC10366731

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.