Evidence map›Paper›PMID 37489149›Full record

ReviewJournal of inflammation research2023

Complex Neuroimmune Involvement in Neurodevelopment: A Mini-Review.

Marianne C Monet, Ning Quan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of inflammation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marianne C MonetStiles-Nicholson Brain Institute, Florida Atlantic University, Jupiter, FL, USA.ORCID 0000-0001-8917-5680
Ning QuanDepartment of Biomedical Science, Charles E. Schmidt College of Medicine, Jupiter, FL, USA.ORCID 0000-0001-7223-8593
Florida Atlantic University · USJupiter Medical Center · US

Funding

Neuroinflammation, Neuronal IL-1R1, and BehaviorR01NS116914 · NINDS · FLORIDA ATLANTIC UNIVERSITY · PI Ning Quan · 2020 to 2026
$2.2M
NINDS NIH HHS R01 NS116914
6 · The paper itself

Abstract

It is increasingly evident that cells and molecules of the immune system play significant roles in neurodevelopment. As perinatal infection is associated with the development of neurodevelopmental disorders, previous research has focused on demonstrating that the induction of neuroinflammation in the developing brain is capable of causing neuropathology and behavioral changes. Recent studies, however, have revealed that immune cells and molecules in the brain can influence neurodevelopment without the induction of overt inflammation, identifying neuroimmune activities as integral parts of normal neurodevelopment. This mini-review describes the shift in literature that has moved from emphasizing the intrusion of inflammatory events as a main culprit of neurodevelopmental disorders to evaluating the deviation of the normal neuroimmune activities in neurodevelopment as a potential pathogenic mechanism.

Indexed as

cytokineglianeurodevelopmental disordersneuroinflammation

Identifiers

PMID37489149
PMCPMC10363380
OpenAlexW4384830773

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.