Evidence map›Paper›PMID 37489009›Full record

ArticleActa biochimica et biophysica Sinica2023

Efficient splicing of the CPE intein derived from directed evolution of the

Qin Zhan, Changhua Shi, Yu Jiang, Xianling Gao, Ying Lin

Open access · diamondAbstract read
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Qin ZhanCollege of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.
Changhua ShiCollege of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.
Yu JiangCollege of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.
Xianling GaoShandong Guoli Biotechnology Co., Ltd., Jinan 250101, China.
Ying LinCollege of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China.
Donghua University · CNKai Biotech (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intein-mediated protein splicing has been widely used in protein engineering; however, the splicing efficiency and extein specificity usually limit its further application. Thus, there is a demand for more general inteins that can overcome these limitations. Here, we study the

Indexed as

Cryptococcus neoformansInteinsProtein SplicingDirected Molecular EvolutionProtein EngineeringProteinsProteinsC-exteindirected evolutionPRP8 intein

Identifiers

PMID37489009
PMCPMC10448054
OpenAlexW4384207031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.