Evidence map›Paper›PMID 37488765›Full record

ReviewCurrent medicinal chemistry2024

Anti-gout and Urate-lowering Potentials of Curcumin: A Review from Bench to Beside.

Amir Masoud Jafari-Nozad, Amirsajad Jafari, Saman Yousefi, Hasan Bakhshi, Tahereh Farkhondeh, Saeed Samarghandian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Amir Masoud Jafari-NozadStudent Research Committee, Birjand University of Medical Sciences, Birjand, Iran.
Amirsajad JafariDepartment of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Saman YousefiFaculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
Hasan BakhshiVector-borne Diseases Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran.
Tahereh FarkhondehDepartment of Toxicology and Pharmacology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran.
Saeed SamarghandianHealthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur 9318614139, Iran.
University of Neyshabur · IRBirjand University of Medical Sciences · IRIslamic Azad University of Shahrekord · IRNorth Khorasan University of Medical Sciences · IRShiraz University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGouty arthritis is a complex form of inflammatory arthritis, triggered by the sedimentation of monosodium urate crystals in periarticular tissues, synovial joints, and other sites in the body. Curcumin is a natural polyphenol compound, isolated from the rhizome of the plant

objectiveThis study aimed to discuss the beneficial impacts of curcumin and its mechanism in treating gout disease.

methodsTen English and Persian databases were used to conduct a thorough literature search. Studies examining the anti-gouty arthritis effects of curcumin and meeting the inclusion criteria were included.

resultsAccording to the studies, curcumin has shown xanthine oxidase and urate transporter- 1 inhibitory properties, uric acid inhibitory characteristics, and antioxidant and anti- inflammatory effects. However, some articles found no prominent reduction in uric acid levels.

conclusionIn this review, we emphasized the potency of curcumin and its compounds against gouty arthritis. Despite the potency, we suggest an additional well-designed evaluation of curcumin, before its therapeutic effectiveness is completely approved as an antigouty arthritis agent.

Indexed as

Arthritis, GoutyCurcuminUric AcidAnimalsAnti-Inflammatory AgentsAntioxidantsGoutGout SuppressantsHumansXanthine OxidaseAnti-Inflammatory AgentsAntioxidantsCurcuminGout SuppressantsUric AcidXanthine OxidaseArthritisCurcuma longa.curcumingoutjoint diseasesuric acid

Identifiers

PMID37488765
OpenAlexW4385231084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.