ArticleJournal of health, population, and nutrition2023
Association between serum iron and liver transaminases based on a large adult women population.
Article in Journal of health, population, and nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Hyperferritinemia Is Associated with Higher Adiposity, Metabolic Syndrome, and Hepatic Dysfunction, Mainly Affecting Men: A Study in Southern Brazil.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025Article
- Study of the relationship between iron metabolism disorders and sepsis-associated liver injury: A prospective observational study.World journal of gastroenterology · 2025Observational
- Anemia and its association with glycemia and transaminitis in patients with type 2 diabetes mellitus: A cross-sectional pilot study.Journal of family medicine and primary care · 2024Article
- Article
- THE CLINICAL SIGNIFICANCE OF COMPLETE BLOOD COUNT, NEUTROPHIL-TO-LYMPHOCYTE RATIO, AND MONOCYTE-TO-LYMPHOCYTE RATIO IN GESTATIONAL DIABETES MELLITUS.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies are being focused on the potential roles of iron in various diseases, but remain unclear for the association between serum iron and liver injury, especially in adult women.
methodsBased on the National Health and Nutrition Examination Survey, we investigated the relationship between serum iron and alanine aminotransferase (ALT) and aspartate aminotransferase (AST) among 19,185 adult women.
resultsUsing weighted multivariate regression analyses, subgroup analyses, and threshold effect analyses, we found that serum iron was independently and positively correlated with ALT and AST. These associations differed in various age or race. Additionally, we found turning points in the curves of the relationship between serum iron and ALT in all women and the non-pregnant women. Using sensitivity analyses, we further found that the associations between serum iron and the liver transaminases remained positive in the non-pregnant women after adjusting for various covariates, but not in pregnant women. Besides, the positive associations between them kept present after excluding the women with high blood pressure, diabetes, and chronic kidney disease.
conclusionThe present study indicated a positive association between serum iron and liver transaminases, indicating that serum iron may be a potential biomarker of liver function.
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