Evidence map›Paper›PMID 37488659›Full record

ArticleIMA fungus2023

Human adaptation and diversification in the Microsporum canis complex.

Xin Zhou, Sarah A Ahmed, Chao Tang, Maria Eduarda Grisolia, José Francisco Ghignatti Warth, Kristen Webster, Andrea Peano, Silke Uhrlass, Claudia Cafarchia, Marie Pierre Hayette and 5 more

Open access · goldAbstract read
In one paragraph

Article in IMA fungus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Canine dermatophytic kerion caused byFrontiers in veterinary science · 2026
    Article
  5. Article
  6. Review
  7. mBio · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 6 countries.

Xin ZhouCenter of Expertise in Mycology of Radboud University Medical Center, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0003-2094-7288
Sarah A AhmedCenter of Expertise in Mycology of Radboud University Medical Center, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0003-0155-8113
Chao TangCenter of Expertise in Mycology of Radboud University Medical Center, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
Maria Eduarda GrisoliaBioprocess Engineering and Biotechnology, Federal University of Paraná, Curitiba, Brazil.ORCID http://orcid.org/0000-0003-1843-052X
José Francisco Ghignatti WarthMicrobiology, Parasitology and Pathology Graduate Program, Federal University of Paraná, Curitiba, Brazil.
Kristen WebsterDepartment of Dermatology, Center for Medical Mycology, University Hospitals, Cleveland, USA.
Andrea PeanoDepartment of Veterinary Sciences, University of Turin, Grugliasco, Italy.
Silke UhrlassLabor für Medizinische Mikrobiologie Nenoff / Krüger, Mölbis, Germany.
Claudia CafarchiaDepartment of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.ORCID http://orcid.org/0000-0002-5632-4472
Marie Pierre HayetteBelgian National Reference Center, Clinical Microbiology, University Hospital of Liege, Liege, Belgium.
Rosalie SacheliBelgian National Reference Center, Clinical Microbiology, University Hospital of Liege, Liege, Belgium.
Tadeja MatosMedical Faculty, Institute of Microbiology and Immunology, University of Ljubljana, Ljubljana, Slovenia.
Yingqian KangKey Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education of Guizhou & Guizhou Talent Base for Microbiology and Human Health, School of Basic Medical Sciences, Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, Guizhou Medical University, Guiyang, China. 449164105@qq.com.
G Sybren de HoogCenter of Expertise in Mycology of Radboud University Medical Center, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands. sybren.dehoog@radboudumc.nl.ORCID http://orcid.org/0000-0002-5344-257X
Peiying FengDepartment of Dermatology, 3rd Affiliated Hospital, Sun Yat-senen University, Guangzhou, China. fengpeiying77@163.com.ORCID http://orcid.org/0000-0002-7284-2034
Radboud University Nijmegen · NLUniversidade Federal do Paraná · BRGuiyang Medical University · CNKrüger (Germany) · DESun Yat-sen University · CNUniversity of Bari Aldo Moro · ITUniversity of Ljubljana · SIUniversity of Turin · IT

Funding

CAPES-PrInt No.88887.311835/2018- 00China Scholarship Council No.202006380049Natural Science Foundation of Guangdong Province No.2020A1515011183
6 · The paper itself

Abstract

The Microsporum canis complex consists of one zoophilic species, M. canis, and two anthropophilic species, M. audouinii and M. ferrugineum. These species are the most widespread zoonotic pathogens causing dermatophytosis in cats and humans worldwide. To clarify the evolutionary relationship between the three species and explore the potential host shift process, this study used phylogenetic analysis, population structure analysis, multispecies coalescent analyses, determination of MAT idiomorph distribution, sexual crosses, and macromorphology and physicochemical features to address the above questions. The complex of Microsporum canis, M. audouinii and M. ferrugineum comprises 12 genotypes. MAT1-1 was present only in M. canis, while the anthropophilic entities contained MAT1-2. The pseudocleistothecia were yielded by the mating behaviour of M. canis and M. audouinii. Growth rates and lipase, keratinolysis and urea hydrolytic capacities of zoophilic M. canis isolates were all higher than those of anthropophilic strains; DNase activity of M. ferrugineum exceeded that of M. canis. The optimum growth temperature was 28 °C, but 22 °C favoured the development of macroconidia. Molecular data, physicochemical properties and phenotypes suggest the adaptation of zoophilic M. canis to anthropophilic M. ferrugineum, with M. audouinii in an intermediate position.

Indexed as

DermatophytesHost shiftMAT idiomorph distributionPhylogenyPhysicochemical featuresTinea capitis

Identifiers

PMID37488659
PMCPMC10367411
OpenAlexW4385191690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.