Evidence map›Paper›PMID 37488524›Full record

ArticleMolecular medicine (Cambridge, Mass.)2023

Knockdown of DEC2 expression inhibits the proliferation of mesangial cells through suppressed glycolysis and p38 MAPK/Erk pathway in lupus nephritis.

Huimeng Qi, Li Xu, Qiang Liu

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Molecular medicine (Cambridge, Mass.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. HE4: a potential diagnostic biomarker in autoimmune diseases.Central-European journal of immunology · 2026
    Review
  5. Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Huimeng QiDepartment of General Practice, Fuyang Hospital of Anhui Medical University, Fuyang, 236000, Anhui Province, China.
Li XuDepartment of Nephrology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong Province, China.
Qiang LiuDepartment of Nephrology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong Province, China. liuqiang@ahmu.edu.cn.ORCID http://orcid.org/0000-0002-3351-4038
Guangdong Provincial People's Hospital · CNAnhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo elucidate the mechanism by which DEC2 modulates the proliferation of mesangial cells (MCs) in lupus nephritis (LN).

methodsThe 32-week-old female Fcgr2b

resultsDEC2 was found overexpressed in the kidney of Fcgr2b

conclusionKnockdown of DEC2 expression inhibits the proliferation of MCs through suppressed glycolysis and p38 MAPK/ERK pathway in LN.

Indexed as

Lupus NephritisAnimalsCell ProliferationFemaleGlucoseGlucose Transporter Type 1GlycolysisLactic AcidMAP Kinase Signaling SystemMesangial CellsMiceToll-Like Receptor 4GlucoseGlucose Transporter Type 1Lactic AcidToll-Like Receptor 4BioenergeticsDEC2GlycolysisLupus nephritisMesangial cells

Identifiers

PMID37488524
PMCPMC10364423
OpenAlexW4385222933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.