Evidence map›Paper›PMID 37488472›Full record

ArticleBMC cardiovascular disorders2023

Cardiovascular health profiles in adolescents being born term or preterm-results from the EVA-Tyrol study.

Christoph Hochmayr, Jean-Pierre Ndayisaba, Nina Gande, Anna Staudt, Benoit Bernar, Katharina Stock, Sophia Zollner-Kiechl, Ralf Geiger, Elke Griesmaier, Michael Knoflach and 2 more

Open access · goldAbstract readControlled Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 citations in OpenAlex.

  1. Long-term pulmonary outcomes in BPD throughout the life-course.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  2. Review
  3. Review
  4. [Growth in preterm infants and its relationship with metabolic profile and diet].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Observational
  5. [The association between preterm birth and hypertension].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Christoph HochmayrDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Anichstraße 35, Innsbruck, 6020, Austria.
Jean-Pierre NdayisabaDepartment of Neurology, Medical University of Innsbruck, Anichstraße 35, Innsbruck, 6020, Austria.
Nina GandeDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Anichstraße 35, Innsbruck, 6020, Austria.
Anna StaudtDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Anichstraße 35, Innsbruck, 6020, Austria.
Benoit BernarVASCage, Center on Clinical Stroke Research, Tyrol, Innsbruck, Austria.
Katharina StockVASCage, Center on Clinical Stroke Research, Tyrol, Innsbruck, Austria.
Sophia Zollner-KiechlVASCage, Center on Clinical Stroke Research, Tyrol, Innsbruck, Austria.
Ralf GeigerDepartment of Pediatrics III (Pediatric Cardiology, Allergology and Cystic Fibrosis), Medical University of Innsbruck, Innsbruck, Austria.
Elke GriesmaierDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Anichstraße 35, Innsbruck, 6020, Austria.
Michael KnoflachVASCage, Center on Clinical Stroke Research, Tyrol, Innsbruck, Austria. michael.knoflach@i-med.ac.at.
Ursula Kiechl-KohlendorferDepartment of Pediatrics II (Neonatology), Medical University of Innsbruck, Anichstraße 35, Innsbruck, 6020, Austria. ursula.kohlendorfer@i-med.ac.at.
Early Vascular Ageing (EVA) Study Group
Innsbruck Medical University · ATVASCage · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPreterm birth has been linked with an increased risk of cardiovascular (CV) disease from childhood into adolescence and early adulthood. In this study, we aimed to investigate differences in CV health profiles between former term- and preterm-born infants in a cohort of Tyrolean adolescents.

methodsThe Early Vascular Aging (EVA)-Tyrol study is a population-based non-randomized controlled trial, which prospectively enrolled 14- to 19-year-old adolescents in North Tyrol, Austria and South Tyrol, Italy between 2015 and 2018. Metrics of CV health (body mass index (BMI), systolic (SBP) and diastolic blood pressure (DBP), smoking, physical activity, dietary patterns, total cholesterol and fasting blood glucose) were assessed and compared between former term- and preterm-born girls and boys.

resultsIn total, 1,491 study participants (59.5% female, mean age 16.5 years) were included in the present analysis. SBP and DBP were significantly higher in former preterm-born adolescents (mean gestational age 34.6 ± 2.4 weeks) compared to term-born controls (p < 0.01). In the multivariate regression analysis these findings remained significant after adjustment for potential confounders in all models. No differences were found in all other CV health metrics. The number of participants meeting criteria for all seven health metrics to be in an ideal range was generally very low with 1.5% in former term born vs. 0.9% in former preterm born adolescents (p = 0.583).

conclusionsPreterm birth is associated with elevated SBP and DBP in adolescence, which was even confirmed for former late preterm-born adolescents in our cohort. Our findings underscore the importance of promoting healthy lifestyles in former term- as well as preterm-born adolescents. In addition, we advise early screening for hypertension and long-term follow-up in the group of preterm-born individuals.

Indexed as

Cardiovascular DiseasesCardiovascular SystemHypertensionPremature BirthAdolescentAdultAustriaChildFemaleHumansInfantInfant, NewbornMaleYoung AdultAdolescentsCardiovascular healthHealth metricsHealth promotionPreterm birthRisk factors

Identifiers

PMID37488472
PMCPMC10367422
OpenAlexW4385214975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.