Evidence map›Paper›PMID 37487751›Full record

ArticleNeurology2023

Demographic Disparities in the Incidence, Clinical Characteristics, and Outcome of Posterior Reversible Encephalopathy Syndrome in the United States.

Fadar Oliver Otite, Smit D Patel, Nnabuchi Anikpezie, Haydn Hoffman, Timothy Beutler, Emmanuel Oladele Akano, Ehimen Aneni, Oluwatomi Lamikanra, Chukwuemeka Osondu, Claribel Wee and 6 more

Open access · greenAbstract read
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Factors associated with mortality in posterior reversible encephalopathy syndrome: a nationwide analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Fadar Oliver OtiteFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore. oliverotite@gmail.com.ORCID 0000-0003-2167-5034
Smit D PatelFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Nnabuchi AnikpezieFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.ORCID 0000-0002-6548-0346
Haydn HoffmanFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Timothy BeutlerFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Emmanuel Oladele AkanoFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Ehimen AneniFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Oluwatomi LamikanraFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Chukwuemeka OsonduFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Claribel WeeFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Devin BurkeFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Karen C AlbrightFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Julius G LatorreFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Luis MejicoFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Priyank KhandelwalFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.
Seemant ChaturvediFrom the Department of Neurology (F.O.O., C.W., D.B., K.C.A., J.G.L., L.M.), SUNY Upstate Medical University, Syracuse, NY; Department of Neurosurgery (S.D.P.), University of Connecticut, Hartford; Department of Population Health (N.A.), University of Mississippi Medical Center, Jackson, MS; Department of Neurosurgery (H.H., T.B.), SUNY Upstate Medical University, Syracuse, NY; Molecular Neuropharmacological Unit (E.O.A.), National Institute of Neurological Disorders and Stroke, Bethesda, MD; Section of Cardiovascular Medicine (E.A.), Department of Internal Medicine, Yale University School of Medicine, New Haven, CT; Department of Critical Care (O.L.), Springfield Clinic, IL; Baptist Health South Florida (C.O.), Miami; Departments of Neurology and Neurosurgery (P.K.), Rutgers University, Newark, NJ; and Department of Neurology (S.C.), University of Maryland, Baltimore.ORCID 0000-0001-8660-7644
SUNY Upstate Medical University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001862 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$12.2M
NCATS NIH HHS KL2 TR001862NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

objectivesTo estimate age-specific, sex-specific, and race-specific incidence of posterior reversible encephalopathy syndrome (PRES) in the United States.

methodsWe conducted a retrospective cohort study using the State Inpatient Database of Florida (2016-2019), Maryland (2016-2019), and New York (2016-2018). All new cases of PRES in adults (18 years or older) were combined with Census data to compute incidence. We evaluated the generalizability of incident estimates to the entire country using the 2016-2019 National Readmissions Database (NRD).

resultsAcross the study period, there were 3,716 incident hospitalizations for PRES in the selected states. The age-standardized and sex-standardized incidence of PRES was 2.7 (95% CI 2.5-2.8) cases/100,000/y. Incidence in female patients was >2 times that of male patients (3.7 vs 1.6 cases/100,000/y, DISCUSSION: The incidence of PRES in the United States is approximately 3/100,000/y, but incidence in female patients is >2 times that of male patients. PRES incidence is higher in Black compared with non-Hispanic White and Hispanic patients.

Indexed as

Posterior Leukoencephalopathy SyndromeAdultFemaleFloridaHospitalizationHumansIncidenceMaleRetrospective StudiesUnited States

Identifiers

PMID37487751
PMCPMC10585693
OpenAlexW4385215542

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