Evidence map›Paper›PMID 37487694›Full record

ReviewHeart (British Cardiac Society)2024

Ebstein's anomaly in children and adults: multidisciplinary insights into imaging and therapy.

Giulia Pasqualin, Antonio Boccellino, Massimo Chessa, Giuseppe Ciconte, Cecilia Marcolin, Emanuele Micaglio, Carlo Pappone, Francesco Sturla, Alessandro Giamberti

Open access · hybridAbstract readReview
In one paragraph

Review in Heart (British Cardiac Society), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Prenatal sonographic spectrum and first-trimester diagnostic features of Ebstein anomaly: A descriptive case series.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  3. Article
  4. Article
  5. Risk factors for morbidity and mortality in Ebstein's anomaly: a registry-based study of 398 patients.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  6. Article
  7. Article
  8. Primary Tricuspid Regurgitation in ACHD: Diagnosis and Treatment.Methodist DeBakey cardiovascular journal · 2026
    Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Lithium-induced Ebstein's Anomaly.Heart views : the official journal of the Gulf Heart Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Giulia PasqualinPediatric and Adult Congenital Disease Heart Centre, IRCCS Policlinico San Donato, San Donato Milanese, Italy Giulia.Pasqualin@grupposandonato.it.ORCID 0000-0002-3362-4501
Antonio BoccellinoArrhythmia and Electrophysiology Department, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Massimo ChessaPediatric and Adult Congenital Disease Heart Centre, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0001-7432-4815
Giuseppe CiconteArrhythmia and Electrophysiology Department, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0001-7886-5467
Cecilia MarcolinFaculty of Medicine and Surgery, Vita-Salute San Raffaele University, Milano, Italy.
Emanuele MicaglioArrhythmia and Electrophysiology Department, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0002-8298-7800
Carlo PapponeArrhythmia and Electrophysiology Department, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0002-0901-6135
Francesco Sturla3D and Computer Simulation Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0001-7317-304X
Alessandro GiambertiDepartment of Congenital Cardiac Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
IRCCS Policlinico San Donato · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although survival has significantly improved in the last four decades, the diagnosis of Ebstein's anomaly is still associated with a 20-fold increased risk of mortality, which generally drops after neonatal period and increases subtly thereafter. With increasing age of presentation, appropriate timing of intervention is challenged by a wide spectrum of disease and paucity of data on patient-tailored interventional strategies. The present review sought to shed light on the wide grey zone of post-neonatal Ebstein's manifestations, highlighting current gaps and achievements in knowledge for adequate risk assessment and appropriate therapeutic strategy.A 'wait-and-see' approach has been adopted in many circumstances, though its efficacy is now questioned by the awareness that Ebstein's anomaly is not a benign disease, even when asymptomatic. Moreover, older age at intervention showed a negative impact on post-surgical outcome.In order to tackle the extreme heterogeneity of Ebstein's anomaly, this review displays the multimodality imaging assessment necessary for a proper anatomical classification and the multidisciplinary approach needed for a comprehensive risk stratification and monitoring strategy. Currently available predictors of clinical outcome are summarised for both operated and unoperated patients, with the aim of supporting the decisional process on the choice of appropriate therapy and optimal timing for intervention.

Indexed as

Ebstein AnomalyAdultChildHumansInfant, NewbornMultimodal ImagingRisk AssessmentArrhythmias, CardiacCongenital AbnormalitiesDiagnostic ImagingGeneticsHeart Defects, Congenital

Identifiers

PMID37487694
PMCPMC10850734
OpenAlexW4385213103

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.