Evidence map›Paper›PMID 37487539›Full record

ArticleThe Journal of infectious diseases2023

The Human Blood Fluke, Schistosoma mansoni, Harbors Bacteria Throughout the Parasite's Life Cycle.

Fabio Formenti, Alba Cortés, Michela Deiana, Susannah Salter, Julian Parkhill, Matt Berriman, Gabriel Rinaldi, Cinzia Cantacessi

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Pathogens (Basel, Switzerland) · 2026
    Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Fabio FormentiDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
Alba CortésDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
Michela DeianaIRCCS Sacro Cuore Don Calabria Hospital, Verona, Italy.
Susannah SalterDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
Julian ParkhillDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
Matt BerrimanWellcome Trust Sanger Institute, Hinxton, United Kingdom.
Gabriel RinaldiWellcome Trust Sanger Institute, Hinxton, United Kingdom.
Cinzia CantacessiDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-6863-2950
University of Cambridge · GBAberystwyth University · GBOspedale Sacro Cuore Don Calabria · ITUniversitat de València · ESWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While symbiotic relationships between invertebrates and bacteria have been extensively described, studies of microbial communities inhabiting parasitic worms remain scarce. Exploring the microbiota associated with helminths responsible for major infectious diseases will inform on parasite biology, host-pathogen interactions, and disease pathophysiology. We investigated the presence of microorganisms inhabiting tissues of the human parasite Schistosoma mansoni. In situ hybridization using a pan-bacterial 16S rRNA gene probe revealed bacteria colonizing key developmental stages that were successfully removed after antibiotic treatment of live parasites. Understanding the composition and function of the S. mansoni-associated microbiota may lead to the development of novel microbiome-targeting control strategies.

Indexed as

HelminthsParasitesSchistosomiasis mansoniAnimalsBacteriaHumansLife Cycle StagesRNA, Ribosomal, 16SSchistosoma mansoniRNA, Ribosomal, 16Sfluorescence in situ hybridizationparasite-associated microbiotaschistosomes

Identifiers

PMID37487539
PMCPMC10629713
OpenAlexW4385188849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.