Evidence map›Paper›PMID 37487095›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Resolvin D1 prevents injurious neutrophil swarming in transplanted lungs.

Wenjun Li, Hailey M Shepherd, Yuriko Terada, Ashley E Shay, Amit I Bery, Andrew E Gelman, Kory J Lavine, Charles N Serhan, Daniel Kreisel

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Tissue-resident CCR2Cell reports · 2025
    Article
  10. Article
  11. Review
  12. Immunomodulation by allograft endothelial cells.Frontiers in transplantation · 2025
    Review
  13. Article
  14. Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Wenjun LiDivision of Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-1923-5016
Hailey M ShepherdDivision of Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, MO 63110.
Yuriko TeradaDivision of Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0003-1598-9360
Ashley E ShayDepartment of Anesthesiology, Perioperative, and Pain Medicine, Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.
Amit I BeryDepartment of Medicine, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-1020-8839
Andrew E GelmanDivision of Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, MO 63110.
Kory J LavineDepartment of Medicine, Washington University in St. Louis, St. Louis, MO 63110.
Charles N SerhanDepartment of Anesthesiology, Perioperative, and Pain Medicine, Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-4627-8545
Daniel KreiselDivision of Cardiothoracic Surgery, Department of Surgery, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-7711-8651
Washington University in St. Louis · USBrigham and Women's Hospital · US

Funding

The Role of Neutrophils in Regulating Lung Transplant ToleranceP01AI116501 · NIAID · WASHINGTON UNIVERSITY · PI Daniel Kreisel · 2015 to 2026
$19.4M
THE ROLE OF ISCHEMIA REPERFUSION INJURY IN LUNG ALLOGRAFT REJECTIONR01HL094601 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Daniel Kreisel · 2009 to 2026
$6.9M
Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureR35HL161185 · NHLBI · WASHINGTON UNIVERSITY · PI Kory J. Lavine · 2022 to 2026
$4.3M
Evaluating Resolution Mechanisms for Infectious InflammationR35GM139430 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI SERHAN, CHARLES NICHOLAS · 2021 to 2025
$3.6M
The Role of Donor Innate Immune Responses in Regulating Alloimmunity after Heart TransplantationR01HL151078 · NHLBI · WASHINGTON UNIVERSITY · PI KREISEL, DANIEL, LAVINE, KORY J. · 2020 to 2023
$2.6M
Leukocyte trafficking in thoracic graftsI01BX002730 · VA · ST. LOUIS VA MEDICAL CENTER · PI KREISEL, DANIEL · 2016 to 2025
–
BLRD VA I01 BX002730NHLBI NIH HHS R01 HL094601NHLBI NIH HHS R01HL094601NHLBI NIH HHS R01 HL151078NHLBI NIH HHS R01HL151078NHLBI NIH HHS R35 HL161185NIAID NIH HHS 1P01AI116501NIAID NIH HHS P01 AI116501NIAID NIH HHS U01163086-01NIGMS NIH HHS R35 GM1 39430NIGMS NIH HHS R35 GM139430VA 1I01BX002730
6 · The paper itself

Abstract

Neutrophils are the primary cell type involved in lung ischemia-reperfusion injury (IRI), which remains a frequent and morbid complication after organ transplantation. Endogenous lipid mediators that become activated during acute inflammation-resolution have gained increasing recognition for their protective role(s) in promoting the restoration of homeostasis, but their influence on early immune responses following transplantation remains to be uncovered. Resolvin D1, 7

Indexed as

Docosahexaenoic AcidsOrgan TransplantationAnimalsHumansLungMiceNeutrophilsDocosahexaenoic Acidsresolvin D1inflammationleukocyteslipid mediatorsspecialized proresolving mediatorstransplantation

Identifiers

PMID37487095
PMCPMC10400944
OpenAlexW4385191078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.