Evidence map›Paper›PMID 37487086›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

An activator of voltage-gated K

Ilenio Servettini, Giuseppe Talani, Alfredo Megaro, Maria Dolores Setzu, Francesca Biggio, Michelle Briffa, Luca Guglielmi, Nicoletta Savalli, Francesca Binda, Francis Delicata and 11 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Selective loss and transcriptional reprogramming of Nox4The journal of headache and pain · 2025
    Article
  7. Review
  8. Improving plant breeding through AI-supported data integration.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  9. A conifer metabolite corrects episodic ataxia type 1 by voltage sensor-mediated ligand activation of Kv1.1.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Review
  11. A novelFrontiers in cellular neuroscience · 2024
    Article
  12. Genetic Background of Epilepsy and Antiepileptic Treatments.International journal of molecular sciences · 2023
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 12 institutions in 8 countries.

Ilenio ServettiniSection of Physiology, Department of Medicine, University of Perugia, Perugia 06123, Italy.ORCID 0000-0002-6163-7975
Giuseppe TalaniInstitute of Neuroscience, National Research Council, Monserrato 09042, Italy.ORCID 0000-0002-7642-557X
Alfredo MegaroSection of Physiology, Department of Medicine, University of Perugia, Perugia 06123, Italy.ORCID 0009-0006-3148-9568
Maria Dolores SetzuDepartment of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy.ORCID 0000-0002-6934-4042
Francesca BiggioDepartment of Life and Environmental Sciences, University of Cagliari, Monserrato 09042, Italy.
Michelle BriffaDepartment of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida MSD2080, Malta.ORCID 0000-0002-1911-8709
Luca GuglielmiMedical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom.
Nicoletta SavalliDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
Francesca BindaDepartment of Fundamental Neurosciences, University of Lausanne, Lausanne 1011, Switzerland.
Francis DelicataCollege of Pharmacy, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB R3E 0T5, Canada.
Gilles Bru-MercierDepartment of Physiology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain 17666, United Arab Emirates.ORCID 0000-0001-9794-9295
Neville VassalloDepartment of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida MSD2080, Malta.ORCID 0000-0002-8985-5587
Vittorio MaglioneIstituto di Ricovero e Cura a Carattere Scientifico Neuromed, Pozzilli 86077, Italy.ORCID 0000-0002-6906-7372
Ruben J CauchiDepartment of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida MSD2080, Malta.ORCID 0000-0001-6150-1608
Alba Di PardoIstituto di Ricovero e Cura a Carattere Scientifico Neuromed, Pozzilli 86077, Italy.
Maria ColluDepartment of Biomedical Sciences, University of Cagliari, Monserrato 09042, Italy.
Paola ImbriciDepartment of Pharmacy-Drug Sciences, University of Bari ''Aldo Moro", 70125 Bari, Italy.ORCID 0000-0001-9140-5350
Luigi CatacuzzenoDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia 06123, Italy.
Maria Cristina D'AdamoDepartment of Medicine and Surgery, Libera Università Mediterranea ''Giuseppe DEGENNARO", Casamassima 70010, Italy.ORCID 0000-0002-6758-6064
Riccardo OlceseDepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095.
Mauro PessiaDepartment of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida MSD2080, Malta.ORCID 0000-0002-2857-6795
University of Malta · MTUniversity of Cagliari · ITUniversity of Perugia · ITIstituto Neurologico Mediterraneo · ITUniversity of California, Los Angeles · USInstitut des Neurosciences Cellulaires et Intégratives · FRLUM Jean Monnet University · ITMRC Laboratory of Molecular Biology · GBNational Research Council · ITUnited Arab Emirates University · AEUniversity of Bari Aldo Moro · ITUniversity of Manitoba · CA

Funding

The Molecular Transitions that Initiate EC Coupling in Skeletal MuscleR35GM131896 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OLCESE, RICCARDO · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM131896NIGMS NIH HHS R35GM131896
6 · The paper itself

Abstract

Loss-of-function mutations in the

Indexed as

MyokymiaAnimalsAtaxiaDrosophilaDrosophila melanogasterKv1.2 Potassium ChannelMiceKv1.2 Potassium Channelepisodic ataxia type 1Kv1.1(KCNA1)Kv1.2(KCNA2)niflumic acidOMIM160120

Identifiers

PMID37487086
PMCPMC10401004
OpenAlexW4385191046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.