SynthesisReviews in endocrine & metabolic disorders2023
Phase angle as a marker of outcome in hospitalized pediatric patients. A systematic review of the evidence (GRADE) with meta-analysis.
Synthesis in Reviews in endocrine & metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Association between malnutrition diagnosed by different screening and assessment tools and clinical outcomes: an umbrella review.Frontiers in nutrition · 2025Pooled it
- Relationship between low phase angle and impaired healing of diabetic foot ulcer: a retrospective cohort study.Nutrition & metabolism · 2026Article
- Bioelectrical Impedance Phase Angle and its Relationship with Anthropometric and Body Composition Parameters in Hospitalized Children with Severe Acute Malnutrition: A Longitudinal Follow-up Study.Indian pediatrics · 2026Observational
- Exploratory phase angle assessment after atrial fibrillation ablation in overweight patients: a pilot study.BMC cardiovascular disorders · 2026Article
- The trajectories of bioelectrical impedance analysis-derived raw variables (phase angle and impedance ratio) in healthy Italian children and adolescents: a retrospective observational study.European journal of pediatrics · 2026Observational
- Morphofunctional markers to assess disease-related pediatric malnutrition at admission and their association with length of hospital stay.Frontiers in nutrition · 2026Article
- First Phase Angle Update at the National Level Among Koreans: Findings From a Bioelectrical Impedance Analysis and Nutritional Survey Involving Five Thousand Adults.Clinical nutrition research · 2025Article
- Bioelectrical impedance analysis of body composition in children and adolescents with type 1 diabetes: a prospective case-control study.European journal of pediatrics · 2025Article
- Cellular Recovery and Body Composition Changes in Pediatric Celiac Disease After the Start of a Gluten-Free Diet: A Prospective Cohort Study.Journal of clinical medicine · 2025Article
- Association between phase angle and all-cause mortality in adults aged 18-49 years: NHANES 1999-2004.Scientific reports · 2025Article
- Bioelectrical impedance vector analysis and phase angle to verify early hydration status and prognosis in hospitalized children with nephrotic syndrome: an exploratory case series.Frontiers in nutrition · 2025Article
- Establishing percentiles for phase angle, skeletal muscle mass index, and muscle-to-fat ratio in Brazilian adolescents: a bioelectrical impedance analysis study with 59,000 participants.Frontiers in nutrition · 2025Article
- Observational
- Postoperative complications in the pediatric population. Malnutrition or phase angle? Which one do we use?Frontiers in nutrition · 2024Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phase angle (PhA) is a valuable tool for evaluating the nutritional and inflammatory status, which can accompany acute and severe disorders. PhA is a cellular health biomarker, whose value is particularly substantial due to the negative consequences of these situations in the pediatric population. Relevant literature was collected with the aim of comprehensively analysing the evidence on the association between an altered PhA can serve as a predictive-marker for mortality and poor-outcomes in at-risk-pediatric patients. Understanding this relationship could have significant implications for identifying high-risk individuals and implementing timely interventions. A systematic review with meta-analysis was conducted in the primary electronic databases from inception until January 2023. Overall, four studies with a total of 740 patients were eligible for our analysis. Evidence demonstrates that PhA is associated with nutritional status, reflecting undernutrition and changes in body composition related to illness. This review suggests that PhA can indeed be used as an indicator of nutritional status and a tool for predicting prognosis, including mortality and poor-outcomes, in hospitalized pediatric patients. A low PhA was associated with a significant mortality risk [RR:1.51;95%CI (1.22-1.88),p = 0.0002;I2 = 0%,(p = 0.99)] and an increased complications risk [OR:8.17;95%CI (2.44-27.4),p = 0.0007;I2 = 44%,(p = 0.18)]. These findings highlight the importance of taking a comprehensive approach to clinical nutrition, integrating multiple evaluation aspects to establish an accurate diagnosis and personalized therapeutic plans. While PhA emerges as a valuable tool for assessing the risk of malnutrition and as a prognostic-indicator for poor-outcomes in pediatric patients. Further future studies are needed to focus on investigating this relationship in larger and diverse population to strengthen the evidence base.
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