ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Change in health-related quality of life and functional disability over time post-concussion in youth.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study.Neurology. Genetics · 2026Article
- Incidence, risk factors and outcomes of persistent post-concussion symptoms in Singaporean school-going children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Optimal Recovery Following Pediatric Concussion.JAMA network open · 2025Article
- Acceptance and commitment therapy for mild traumatic brain injury (ACTion-mTBI): a quasiexperimental feasibility study.BMJ open · 2025Article
- Delays in Immediate Athletic Training Evaluation Following Concussion Among High School Football Players: A Report from the Athletic Training Practice-Based Research Network.Journal of athletic training · 2025Article
- The Association Between Daily Registrations of Persistent Post-Concussion Symptoms Using an mHealth App and the Retrospective Rivermead Post-Concussion Symptoms Questionnaire.Neurotrauma reports · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
purposeConcussions can have detrimental on children's cognitive, emotional, behavioral, and/or social functioning. We sought to examine changes in health-related quality of life (HRQOL) and functional disability from pre-injury to 1-week post-concussion, and to symptom resolution among youth ages 11-17 with a concussion.
methodsIn this prospective, longitudinal cohort study, 83 concussed youth, ages 11-17, self-reported post-concussion symptoms daily as well as HRQOL and functional disability at baseline (pre-injury, retrospective), 1-week post-concussion, and symptom resolution. We modeled changes in overall and sub-scale HRQOL and functional disability scores over time from pre-injury to 1-week post-concussion and from 1-week post-concussion to symptom resolution using a piecewise linear mixed model, adjusting for potential covariables. Estimated fixed effects with a corresponding adjusted coefficient (beta), along with their 95% confidence intervals are presented.
resultsOverall HRQOL worsened from pre-injury to 1-week post-injury (β = - 5.40, 95%CI - 9.22, - 1.58) but did not change from 1-week post-injury to symptom resolution. Physical HRQOL worsened from pre-injury to 1-week post-injury (β = - 9.90, 95%CI - 14.65, - 5.14) but improved from 1-week post-injury to symptom resolution (β = 1.64, 95%CI 0.50, 2.78), while psychosocial HRQOL showed no change over time. Functional disability worsened from pre-injury to 1-week post-injury (β = 8.36, 95%CI 5.93, 10.79) but with no change from 1-week post-injury to symptom resolution. Youth with symptom duration > 14 days reported worse HRQOL and functional disability than those who recovered in ≤ 14 days and greater daily post-concussion symptom scores were associated with worse HRQOL and functional disability.
conclusionConcussions have a negative impact on overall and physical HRQOL and functional disability in youth acutely post-injury. Ratings of HRQOL could be used to inform clinical treatment decisions to assist with the recovery process.
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