Evidence map›Paper›PMID 37486419›Full record

ReviewArchives of microbiology2023

Therapeutic and immunomodulatory role of probiotics in breast cancer: A mechanistic review.

Muhammad Summer, Shaukat Ali, Umaima Fiaz, Hafiz Muhammad Tahir, Muhammad Ijaz, Shumaila Mumtaz, Rabia Mushtaq, Rida Khan, Hafsa Shahzad, Hashim Fiaz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

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  11. Therapeutic potential of microbiome modulation in reproductive cancers.Medical oncology (Northwood, London, England) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Muhammad SummerDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Shaukat AliDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan. dr.shaukatali@gcu.edu.pk.
Umaima FiazDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Hafiz Muhammad TahirDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Muhammad IjazDepartment of Veterinary Medicine, University of Veterinary and Animal Sciences Lahore, Lahore, Pakistan.
Shumaila MumtazDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Rabia MushtaqDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Rida KhanDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Hafsa ShahzadDepartment of Zoology, Government College University Lahore, Lahore, 54000, Pakistan.
Hashim FiazDepartment of Medicine and Surgery, Ammer-ul-din Medical College Lahore, Lahore, Pakistan.
Government College University, Lahore · PKLahore General Hospital · PKUniversity of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer has become the most prevalent and noxious type of malignancy around the globe (Giaquinto et al., 2022). Multiple clinical strategies including chemotherapy, radiotherapy, and immunotherapy have been in practice to manage breast cancer. Besides the protective roles of conventional remedial approaches, and non-reversible and deteriorative impacts like healthy cell damage, organ failure, etc., the world scientific community is in a continuous struggle to find some alternative biocompatible and comparatively safe solutions. Among novel breast cancer management/treatment options, the role of probiotics has become immensely important. The current review encompasses the prevalence statistics of breast cancer across the globe concerning developed and undeveloped counties, intestinal microbiota linkage with breast cancer, and association of breast microbiome with breast carcinoma. Furthermore, this review also narrates the role of probiotics against breast cancer and their mode of action. In Vivo and In Vitro studies under breast cancer research regarding probiotics are mechanistically explained. The current review systematically explains the immunomodulatory role of probiotics to prevent breast cancer. Last, but not the least, current review concludes the use of probiotics in the treatment of breast cancer through various mechanisms and future recommendations for molecular basis studies.

Indexed as

Breast NeoplasmsGastrointestinal MicrobiomeMicrobiotaProbioticsDysbiosisFemaleHumansCancerImmunomodulatoryMicrobiomeProbiotics

Identifiers

PMID37486419
OpenAlexW4385186016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.