Evidence map›Paper›PMID 37486409›Full record

Trial reportEuropean journal of pediatrics2023

Virtual reality hypnosis for needle-related procedural pain and fear management in children: a non-inferiority randomized trial.

Sharron van den Berg, Maurits O Hoogeveen, Tijn M S van Winden, Malika Chegary, Mehmet S Genco, Nini H Jonkman

Erratum issuedAbstract readRandomized Controlled TrialEquivalence Trial
PubMed Publisher
In one paragraph

Trial report in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sharron van den BergDepartment of Pediatrics, OLVG Hospital, Oosterpark 9, Amsterdam, 1091 AC, The Netherlands. s.vandenberg@olvg.nl.ORCID http://orcid.org/0000-0002-7894-5413
Maurits O HoogeveenDepartment of Pediatrics, OLVG Hospital, Oosterpark 9, Amsterdam, 1091 AC, The Netherlands.
Tijn M S van WindenDepartment of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands.ORCID http://orcid.org/0000-0002-5357-8872
Malika ChegaryDepartment of Pediatrics, OLVG Hospital, Oosterpark 9, Amsterdam, 1091 AC, The Netherlands.ORCID http://orcid.org/0000-0002-1012-4942
Mehmet S GencoDepartment of Pediatrics, OLVG Hospital, Oosterpark 9, Amsterdam, 1091 AC, The Netherlands.
Nini H JonkmanDepartment of Research and Epidemiology, OLVG Hospital, Oosterpark 9, Amsterdam, 1091 AC, The Netherlands.ORCID http://orcid.org/0000-0002-2585-8973
Amsterdam University Medical Centers · NLOLVG · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Needle-related procedures can cause pain and fear in children and may lead to avoidance of future medical care. The aim of this study is to investigate whether virtual reality hypnosis (VRH) is non-inferior to medical hypnosis (MH) by a trained healthcare provider in reducing pain in children. This non-inferiority randomized trial was conducted at a teaching hospital in the Netherlands. Children aged 6 to 18 years were randomized to treatment with VRH or MH. The primary outcome was self-reported pain, using the Wong-Baker FACES Scale (WBFS) with the non-inferiority margin defined as a difference of 1.5 points. Secondary outcomes included observer-reported pain (Numeric Rating Scale), fear (scored by children and observers with the Children's Fear Scale), blood pressure, heart rate, treatment satisfaction, and adverse effects. We randomized 138 children to VRH or MH treatment and included 114 children in the analyses (VRH n = 60, MH n = 54). We found non-inferiority for VRH compared to MH on patient-reported pain (mean difference =  - 0.17, 95%CI - 1.01;0.66). Secondary outcomes were comparable between VRH and MH groups. Both treatments scored high on patient satisfaction (VRH median = 9.0, MH median = 10.0, p = 0.512).

conclusionVRH may be an effective and safe treatment option besides MH for reducing patient-reported pain in children during a needle-related procedure. VRH was non-inferior to MH in patient-reported fear and both treatments were comparable in terms of patient-reported fear, observer-reported pain and fear, physical distress, and patient satisfaction.

trial registrationICTRP https://trialsearch.who.int/ , trial ID NL9385; date registered: 03/04/2021. WHAT IS KNOWN: • Medical hypnosis is effective in reducing procedural distress in children during needle-related procedures. • Virtual reality (VR) is an audiovisual electronic device that guides users into an immersive three-dimensional environment. WHAT IS NEW: • This study shows that VR hypnosis is non-inferior to medical hypnosis in reducing pain and fear in children undergoing a needle-related procedure. • Both VR hypnosis and medical hypnosis were appreciated highly by children to distract them during needle-related procedures.

Indexed as

HypnosisProcedural PainVirtual RealityAdolescentChildFearHumansPainFearHypnosisPainPediatricRandomized controlled trialVirtual reality

Identifiers

PMID37486409
OpenAlexW4385186957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.