Evidence map›Paper›PMID 37486368›Full record

SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2023

Early surgery and number of injured ligaments are associated with postoperative stiffness following multi-ligament knee injury surgery: a systematic review and meta-analysis.

Emre Anil Özbek, Sahil Dadoo, Camila Grandberg, Armin Runer, Ting Cong, Jonathan D Hughes, James J Irrgang, Volker Musahl

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Outcomes after multiligament knee injury worsen over time: A systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Pooled it
  2. Article
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  9. Outcomes of acute versus delayed multi-ligament knee injury reconstruction: A retrospective analysis with mean 3.6-year follow-up.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
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  12. Knee joint dislocations-Current epidemiology and treatment in Germany.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
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  20. Multiligament knee injuries. Ten years' experience at a public university, level I Trauma Center.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Emre Anil ÖzbekDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. anl_ozbek@hotmail.com.ORCID http://orcid.org/0000-0002-8502-9798
Sahil DadooDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Camila GrandbergDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Armin RunerDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Ting CongDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Jonathan D HughesDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
James J IrrgangDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, USA.
Volker MusahlDepartment of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
University of Pittsburgh Medical Center · USAnkara University · TRTUM Klinikum · DEUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo perform a systematic review and meta-analysis to investigate the rate of stiffness after multi-ligament knee injury (MLKI) surgery and identify potential risk factors associated with postoperative stiffness.

methodsThis study was conducted in accordance with the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement. Registration was done on the PROSPERO International Prospective Register of Systematic Reviews (CRD42022321849). A literature search of PubMed, Ovid, Embase, and Cochrane Library databases was conducted in October 2022 for clinical studies reporting postoperative stiffness after MLKI surgery. A quality assessment was performed using the Methodological Index of Non-Randomized Studies (MINORS) grading system. The following variables were extracted from studies for correlation to postoperative stiffness: study characteristics, cohort demographics, Schenk classification, neurovascular injury, mechanism of injury, external fixator placement, timing of surgery, and concomitant knee injuries.

resultsThirty-six studies comprising 4,159 patients who underwent MLKI surgery met the inclusion criteria, including two Level-II, fourteen Level-III, and twenty Level-IV studies. The average MINOR score of the studies was 14. The stiffness rate after MLKI was found to be 9.8% (95% CI 0.07-0.13; p < 0.01; I

conclusionPerforming surgery within the first 3 weeks following MLKI, or concomitant injury of ≥ 3 ligaments, are significantly associated with increased risk of postoperative stiffness. These findings can be utilized by surgeons to decide the timing of surgery for MLKI surgeries especially in which ≥ 3 ligaments are injured. LEVEL OF EVIDENCE: Level IV.

Indexed as

Anterior Cruciate Ligament InjuriesKnee InjuriesSoft Tissue InjuriesVascular System InjuriesHumansLigamentsRisk FactorsACLKnee dislocationMLKIMulti-ligamentPCLStiffness

Identifiers

PMID37486368
OpenAlexW4385186710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.