Evidence map›Paper›PMID 37486125›Full record

ReviewACS nano2023

Aggregation-Induced Emission (AIE), Life and Health.

Haoran Wang, Qiyao Li, Parvej Alam, Haotian Bai, Vandana Bhalla, Martin R Bryce, Mingyue Cao, Chao Chen, Sijie Chen, Xirui Chen and 79 more

Abstract readReview
In one paragraph

Review in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

89 authors.

Haoran WangSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China.ORCID 0000-0001-8859-0348
Qiyao LiSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China.ORCID 0000-0002-4472-1534
Parvej AlamClinical Translational Research Center of Aggregation-Induced Emission, School of Medicine, The Second Affiliated Hospital, School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen (CUHK- Shenzhen), Guangdong 518172, China.ORCID 0000-0001-6534-4953
Haotian BaiBeijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.ORCID 0000-0003-3613-3713
Vandana BhallaDepartment of Chemistry, Guru Nanak Dev University, Amritsar 143005, India.ORCID 0000-0002-8740-1928
Martin R BryceDepartment of Chemistry, Durham University, South Road, Durham DH1 3LE, United Kingdom.ORCID 0000-0003-2097-7823
Mingyue CaoState Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China.
Chao ChenDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Guangdong-Hong Kong-Macau Joint Laboratory of Optoelectronic and Magnetic Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR 999077, China.
Sijie ChenMing Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Sha Tin, Hong Kong SAR 999077, China.
Xirui ChenState Key Laboratory of Food Science and Resources, School of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Yuncong ChenState Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Department of Cardiothoracic Surgery, Nanjing Drum Tower Hospital, Medical School, Nanjing University, Nanjing 210023, China.ORCID 0000-0002-8406-4866
Zhijun ChenEngineering Research Center of Advanced Wooden Materials and Key Laboratory of Bio-based Material Science and Technology of Ministry of Education, Northeast Forestry University, Harbin 150040, China.ORCID 0000-0001-7203-5788
Dongfeng DangSchool of Chemistry, Xi'an Jiaotong University, Xi'an 710049 China.ORCID 0000-0001-9921-9632
Dan DingState Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, and College of Life Sciences, Nankai University, Tianjin 300071, China.ORCID 0000-0003-1873-6510
Siyang DingDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Yanhong DuoDepartment of Radiation Oncology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong 518020, China.ORCID 0000-0003-4569-0933
Meng GaoNational Engineering Research Center for Tissue Restoration and Reconstruction, Key Laboratory of Biomedical Engineering of Guangdong Province, Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education, Innovation Center for Tissue Restoration and Reconstruction, School of Materials Science and Engineering, South China University of Technology, Guangzhou 510006, China.ORCID 0000-0001-8071-8079
Wei HeDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Guangdong-Hong Kong-Macau Joint Laboratory of Optoelectronic and Magnetic Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR 999077, China.
Xuewen HeThe Key Lab of Health Chemistry and Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, 199 Ren'ai Road, Suzhou 215123, China.
Xuechuan HongState Key Laboratory of Virology, Department of Cardiology, Zhongnan Hospital of Wuhan University, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Yuning HongDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.ORCID 0000-0002-8085-1651
Jing-Jing HuState Key Laboratory of Biogeology and Environmental Geology, Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.ORCID 0000-0002-1449-6137
Rong HuSchool of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China.
Xiaolin HuangState Key Laboratory of Food Science and Resources, School of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Tony D JamesDepartment of Chemistry, University of Bath, Bath BA2 7AY, United Kingdom.
Xingyu JiangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Road, Nanshan District, Shenzhen, Guangdong 518055, China.ORCID 0000-0002-5008-4703
Gen-Ichi KonishiDepartment of Chemical Science and Engineering, Tokyo Institute of Technology, O-okayama, Meguro-ku, Tokyo 152-8552, Japan.ORCID 0000-0002-6322-0364
Ryan T K KwokDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Guangdong-Hong Kong-Macau Joint Laboratory of Optoelectronic and Magnetic Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR 999077, China.
Jacky W Y LamDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Guangdong-Hong Kong-Macau Joint Laboratory of Optoelectronic and Magnetic Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR 999077, China.
Chunbin LiCollege of Chemistry and Chemical Engineering, Inner Mongolia Key Laboratory of Fine Organic Synthesis, Inner Mongolia University, Hohhot 010021, China.
Haidong LiState Key Laboratory of Fine Chemicals, School of Bioengineering, Dalian University of Technology, 2 Linggong Road, Dalian 116024, China.ORCID 0000-0002-2721-0337
Kai LiCollege of Chemistry, Zhengzhou University, 100 Science Road, Zhengzhou 450001, China.ORCID 0000-0001-9458-4796
Nan LiKey Laboratory of Macromolecular Science of Shaanxi Province, Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China.ORCID 0000-0003-1091-0086
Wei-Jian LiShanghai Key Laboratory of Green Chemistry and Chemical Processes & Chang-Kung Chuang Institute, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, China.
Ying LiInnovation Research Center for AIE Pharmaceutical Biology, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, China.
Xing-Jie LiangCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.ORCID 0000-0002-4793-1705
Yongye LiangDepartment of Materials Science and Engineering, Shenzhen Key Laboratory of Printed Organic Electronics, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0002-7416-8792
Bin LiuDepartment of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore.ORCID 0000-0002-0956-2777
Guozhen LiuCiechanover Institute of Precision and Regenerative Medicine, School of Medicine, The Chinese University of Hong Kong, Shenzhen (CUHK- Shenzhen), Guangdong 518172, China.ORCID 0000-0002-0556-6404
Xingang LiuDepartment of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore.
Xiaoding LouState Key Laboratory of Biogeology and Environmental Geology, Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, China.ORCID 0000-0002-6556-2034
Xin-Yue LouInternational Joint Research Laboratory of Nano-Micro Architecture Chemistry, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
Liang LuoNational Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.ORCID 0000-0001-9274-1866
Paul R McGonigalDepartment of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
Zong-Wan MaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510006, China.ORCID 0000-0001-7131-1154
Guangle NiuState Key Laboratory of Crystal Materials, Shandong University, Jinan 250100, China.ORCID 0000-0002-5403-6880
Tze Cin OwyongDepartment of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Andrea PucciDepartment of Chemistry and Industrial Chemistry, University of Pisa, Via Moruzzi 13, Pisa 56124, Italy.ORCID 0000-0003-1278-5004
Jun QianState Key Laboratory of Modern Optical Instrumentations, Centre for Optical and Electromagnetic Research, College of Optical Science and Engineering, International Research Center for Advanced Photonics, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0003-2131-3885
Anjun QinState Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou 510640, China.ORCID 0000-0001-7158-1808
Zijie QiuSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China.ORCID 0000-0003-0728-1178
Andrey L RogachDepartment of Materials Science and Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR 999077, China.ORCID 0000-0002-8263-8141
Bo SituDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Kazuo TanakaDepartment of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.
Youhong TangInstitute for NanoScale Science and Technology, College of Science and Engineering, Flinders University, Bedford Park, South Australia 5042, Australia.ORCID 0000-0003-2718-544X
Bingnan WangState Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou 510640, China.
Dong WangCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0001-5137-0771
Jianguo WangCollege of Chemistry and Chemical Engineering, Inner Mongolia Key Laboratory of Fine Organic Synthesis, Inner Mongolia University, Hohhot 010021, China.
Wei WangShanghai Key Laboratory of Green Chemistry and Chemical Processes & Chang-Kung Chuang Institute, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, China.ORCID 0000-0003-2772-305X
Wen-Xiong WangSchool of Energy and Environment and State Key Laboratory of Marine Pollution, City University of Hong Kong, Kowloon, Hong Kong SAR 999077, China.ORCID 0000-0001-9033-0158
Wen-Jin WangMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510006, China.
Xinyuan WangDepartment of Materials Science and Engineering, Shenzhen Key Laboratory of Printed Organic Electronics, Southern University of Science and Technology, Shenzhen 518055, China.
Yi-Feng WangCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Beijing 100190, China.
Shuizhu WuState Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, College of Materials Science and Engineering, South China University of Technology, Wushan Road 381, Guangzhou 510640, China.ORCID 0000-0002-6739-0694
Yifan WuInnovation Research Center for AIE Pharmaceutical Biology, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, China.
Yonghua XiongState Key Laboratory of Food Science and Resources, School of Food Science and Technology, Nanchang University, Nanchang 330047, China.
Ruohan XuSchool of Chemistry, Xi'an Jiaotong University, Xi'an 710049 China.
Chenxu YanKey Laboratory for Advanced Materials and Joint International Research, Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.
Saisai YanCenter for AIE Research, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
Hai-Bo YangShanghai Key Laboratory of Green Chemistry and Chemical Processes & Chang-Kung Chuang Institute, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, China.ORCID 0000-0003-4926-1618
Lin-Lin YangSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China.ORCID 0000-0001-7315-3233
Mingwang YangDepartment of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, Guangdong-Hong Kong-Macau Joint Laboratory of Optoelectronic and Magnetic Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR 999077, China.
Ying-Wei YangInternational Joint Research Laboratory of Nano-Micro Architecture Chemistry, College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.ORCID 0000-0001-8839-8161
Juyoung YoonDepartment of Chemistry and Nanoscience, Ewha Womans University, Seoul 03760, Korea.ORCID 0000-0002-1728-3970
Shuang-Quan ZangCollege of Chemistry, Zhengzhou University, 100 Science Road, Zhengzhou 450001, China.ORCID 0000-0002-6728-0559
Jiangjiang ZhangGuangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Road, Nanshan District, Shenzhen, Guangdong 518055, China.ORCID 0000-0002-9647-5101
Pengfei ZhangGuangdong Key Laboratory of Nanomedicine, Shenzhen, Engineering Laboratory of Nanomedicine and Nanoformulations, CAS Key Lab for Health Informatics, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, University Town of Shenzhen, 1068 Xueyuan Avenue, Shenzhen 518055, China.ORCID 0000-0003-0390-3806
Tianfu ZhangSchool of Biomedical Engineering, Guangzhou Medical University, Guangzhou 511436, China.ORCID 0000-0001-6012-8856
Xin ZhangDepartment of Chemistry, Research Center for Industries of the Future, Westlake University, 600 Dunyu Road, Hangzhou, Zhejiang Province 310030, China.ORCID 0000-0001-6686-1645
Xin ZhangCiechanover Institute of Precision and Regenerative Medicine, School of Medicine, The Chinese University of Hong Kong, Shenzhen (CUHK- Shenzhen), Guangdong 518172, China.ORCID 0000-0001-9938-2747
Na ZhaoKey Laboratory of Macromolecular Science of Shaanxi Province, Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an 710119, China.ORCID 0000-0001-7347-5865
Zheng ZhaoSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China.ORCID 0000-0002-5536-0439
Jie ZhengDepartment of Chemical, Biomolecular, and Corrosion Engineering The University of Akron, Akron, Ohio 44325, United States.ORCID 0000-0003-1547-3612
Lei ZhengDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.ORCID 0000-0003-2576-8780
Zheng ZhengSchool of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei 230009, China.ORCID 0000-0001-9312-6582
Ming-Qiang ZhuWuhan National Laboratory for Optoelectronics, School of Optical and Electronic Information, Huazhong University of Science and Technology, Wuhan 430074, China.ORCID 0000-0002-8886-4166
Wei-Hong ZhuKey Laboratory for Advanced Materials and Joint International Research, Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China.ORCID 0000-0001-9103-166X
Hang ZouDepartment of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Ben Zhong TangSchool of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, China.ORCID 0000-0002-0293-964X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Light has profoundly impacted modern medicine and healthcare, with numerous luminescent agents and imaging techniques currently being used to assess health and treat diseases. As an emerging concept in luminescence, aggregation-induced emission (AIE) has shown great potential in biological applications due to its advantages in terms of brightness, biocompatibility, photostability, and positive correlation with concentration. This review provides a comprehensive summary of AIE luminogens applied in imaging of biological structure and dynamic physiological processes, disease diagnosis and treatment, and detection and monitoring of specific analytes, followed by representative works. Discussions on critical issues and perspectives on future directions are also included. This review aims to stimulate the interest of researchers from different fields, including chemistry, biology, materials science, medicine, etc., thus promoting the development of AIE in the fields of life and health.

Indexed as

Fluorescent DyesLuminescent AgentsDelivery of Health CareDiagnostic ImagingLuminescenceFluorescent DyesLuminescent Agentsaggregation-induced emissionbioimagingbiomedical applicationcombined therapydetectionluminescent materialmonitoringphototheranosticsprecision medicine

Identifiers

PMID37486125
PMCPMC10416578

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.