Evidence map›Paper›PMID 37486070›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2023

Aortic blood pressure and pulse wave indices responses to exercise in peripheral artery disease.

Danielle Jin-Kwang Kim, Zhaohui Gao, Jian Cui, Urs A Leuenberger, Kristen Brandt, Cheryl Blaha, Aimee Cauffman, Faisal Aziz, Lawrence I Sinoway

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Danielle Jin-Kwang KimPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.ORCID 0000-0002-6899-7957
Zhaohui GaoPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Jian CuiPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.ORCID 0000-0002-4015-9484
Urs A LeuenbergerPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Kristen BrandtPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Cheryl BlahaPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Aimee CauffmanPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Faisal AzizPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Lawrence I SinowayPenn State Heart and Vascular Institute, Penn State College of Medicine, Hershey, Pennsylvania, United States.
Penn State Milton S. Hershey Medical Center · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Project 3: Role Played by ASIC, P2X and EP4 Receptors in the Exercise Pressor Reflex in Health and Simulated PADP01HL134609 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2017 to 2021
$9.4M
Exercise pressor reflex in peripheral artery disease: beneficial effects of heating and mechanismsR01HL141198 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CUI, JIAN, LI, JIANHUA · 2019 to 2023
$3.7M
NCATS NIH HHS UL1 TR002014NHLBI NIH HHS P01 HL134609NHLBI NIH HHS R01 HL141198
6 · The paper itself

Abstract

Peripheral artery disease (PAD) refers to obstructed blood flow in peripheral arteries typically due to atherosclerotic plaques. How PAD alters aortic blood pressure and pressure wave propagation during exercise is unclear. Thus, this study examined central blood pressure responses to plantar flexion exercise by investigating aortic pulse wave properties in PAD. Thirteen subjects with PAD and 13 healthy [age-, sex-, body mass index (BMI) matched] subjects performed rhythmic plantar flexion for 14 min or until fatigue (20 contractions/min; started at 2 kg with 1 kg/min increment up to 12 kg). Brachial (oscillometric cuff) and radial (SphygmoCor) blood pressure and derived-aortic waveforms were analyzed during supine rest and plantar flexion exercise. At rest, baseline augmentation index (

Indexed as

Arterial PressurePeripheral Arterial DiseaseBlood PressureExerciseHeart RateHumansPulse Wave Analysisaortic blood pressureaortic pulse waveaugmentation indexcentral blood pressureperipheral artery disease

Identifiers

PMID37486070
PMCPMC10639020
OpenAlexW4385186779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.