Evidence map›Paper›PMID 37486019›Full record

ArticleAnalytical chemistry2023

Paper-Based Analytical Devices for Accurate Assessment of Transferrin Saturation in Diagnosed Clinical Samples from Ischemic Stroke Patients.

Silvia Dortez, Núria DeGregorio-Rocasolano, Mònica Millán, Teresa Gasull, Agustín G Crevillen, Alberto Escarpa

Abstract read
In one paragraph

Article in Analytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Silvia DortezDepartment of Analytical Chemistry, Physical Chemistry and Chemical Engineering, University of Alcala, 28805 Alcala de Henares, Madrid, Spain.ORCID 0000-0002-1999-5605
Núria DeGregorio-RocasolanoCellular and Molecular Neurobiology Research Group, Department of Neurosciences, Germans Trias I Pujol Research Institute (IGTP), 08916 Badalona, Barcelona, Spain.
Mònica MillánDepartment of Neurociences, Germans Trias I Pujol University Hospital, Universitat Autònoma de Barcelona, 08916 Badalona, Barcelona, Spain.
Teresa GasullCellular and Molecular Neurobiology Research Group, Department of Neurosciences, Germans Trias I Pujol Research Institute (IGTP), 08916 Badalona, Barcelona, Spain.ORCID 0000-0002-9321-1741
Agustín G CrevillenDepartment of Analytical Sciences, Faculty of Sciences, Universidad Nacional de Educacion a Distancia (UNED), 28040 Madrid, Spain.ORCID 0000-0002-4470-6502
Alberto EscarpaDepartment of Analytical Chemistry, Physical Chemistry and Chemical Engineering, University of Alcala, 28805 Alcala de Henares, Madrid, Spain.ORCID 0000-0002-7302-0948

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For the first time, a paper-based analytical device (PAD) was developed for the assessment of transferrin saturation (TSAT), which is defined as the ratio between iron bound to transferrin (Tf) and the total iron-binding capacity (TIBC) of Tf. Both parameters were simultaneously measured on the same PAD using ferrozine as a chromophore and a smartphone as the color reader. To this end, Tf was first isolated from serum using anti-Tf immunomagnetic beads to ensure that only the Tf-bound iron was measured, improving the selectivity and accuracy of TSAT assessment. To demonstrate the practical utility of the device, it was validated by analyzing a certified reference material, showing excellent accuracy (

Indexed as

Ischemic StrokeColorHumansIronMobile ApplicationsTransferrinsIronTransferrins

Identifiers

PMID37486019
PMCPMC10448438

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.