Evidence map›Paper›PMID 37485878›Full record

ArticleDiabetes, obesity & metabolism2023

Baseline leptin predicts response to metformin in adolescents with type 1 diabetes and increased body mass index.

Heba M Ismail, Souptik Barua, Johnny Wang, Ashutosh Sabharwal, Ingrid Libman, Fida Bacha, Kristen J Nadeau, Mustafa Tosur, Maria J Redondo

Open access · hybridAbstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Heba M IsmailDepartment of Pediatrics, Indiana University, School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0003-0102-0030
Souptik BaruaDivision of Precision Medicine, Department of Medicine, NYU Grossman School of Medicine, New York, New York, USA.
Johnny WangDepartment of Biosciences, Rice University, Houston, Texas, USA.
Ashutosh SabharwalDepartment of Electrical and Computer Engineering, Rice University, Houston, Texas, USA.
Ingrid LibmanDivision of Pediatric Endocrinology and Diabetes, University of Pittsburgh, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Fida BachaDiabetes & Endocrinology Division, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Kristen J NadeauUniversity of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-0477-3356
Mustafa TosurDiabetes & Endocrinology Division, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Maria J RedondoDiabetes & Endocrinology Division, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA.
Baylor College of Medicine · USRice University · USIndiana University – Purdue University Indianapolis · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Pittsburgh · US

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Cheryl L. Walker · 2019 to 2026
$14.7M
University of Colorado Anschutz Medical Campus DRCP30DK116073 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI PETER J DEMPSEY · 2020 to 2026
$10.8M
Type 1 diabetes genetic risk scores for the diagnosis of diabetes type in children of diverse racial and ethnic backgroundR01DK124395 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI REDONDO, MARIA JOSE · 2021 to 2024
$2.6M
Type 1 Diabetes Genetic Risk Score in TrialNetR01DK121843 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI REDONDO, MARIA JOSE · 2019 to 2023
$2.4M
The Gut Microbiome in Lean and Obese Youth with Type 1 Diabetes and Novel Mechanism of Action of MetforminK23DK129799 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI ISMAIL, HEBATULLAH · 2022 to 2025
$730k
The Next Generation of Innovative Cardiovascular Clinical/Translational ResearchersK24HL145076 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI NADEAU, KRISTEN JANE · 2019 to 2023
$574k
Doris Duke Charitable Foundation 2021258NHLBI NIH HHS K24 HL145076NIDDK NIH HHS DK097512NIDDK NIH HHS DK121843NIDDK NIH HHS DK124395NIDDK NIH HHS K23 DK129799NIDDK NIH HHS K23DK129799NIDDK NIH HHS P30 DK097512NIDDK NIH HHS P30 DK116073NIDDK NIH HHS R01 DK121843NIDDK NIH HHS R01 DK124395
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1Insulin ResistanceMetforminAdolescentBody Mass IndexHumansHypoglycemic AgentsInsulinLeptinHypoglycemic AgentsInsulinLeptinMetformininsulin resistancemetforminobesity therapytype 1 diabetes

Identifiers

PMID37485878
PMCPMC10592422
OpenAlexW4385186826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.