Evidence map›Paper›PMID 37485869›Full record

ArticleJournal of medicinal chemistry2023

Design, Synthesis, and Evaluation of Novel Δ

Souvik Sarkar, Anne E Mayer Bridwell, James A D Good, Erin R Wang, Samuel R McKee, Joy Valenta, Gregory A Harrison, Kelly N Flentie, Frederick L Henry, Torbjörn Wixe and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 3 countries.

Souvik SarkarDepartment of Chemistry, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0003-1803-2708
Anne E Mayer BridwellDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
James A D GoodDepartment of Chemistry, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0003-2377-030X
Erin R WangDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Samuel R McKeeDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Joy ValentaDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Gregory A HarrisonDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Kelly N FlentieDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Frederick L HenryDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Torbjörn WixeDepartment of Chemistry, Umeå University, SE-90187 Umeå, Sweden.
Peter DemirelDepartment of Chemistry, Umeå University, SE-90187 Umeå, Sweden.
Siva K VagoluDepartment of Microbiology, University of Oslo, N-0316 Oslo, Norway.
Jonathan ChatagnonUniversity Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, 59000 Lille, France.
Arnaud MachelartUniversity Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, 59000 Lille, France.
Priscille BrodinUniversity Lille, CNRS, INSERM, CHU Lille, Institut Pasteur de Lille, U1019-UMR 9017-CIIL-Center for Infection and Immunity of Lille, 59000 Lille, France.ORCID 0000-0003-0991-7344
Tone TønjumDepartment of Microbiology, University of Oslo, N-0316 Oslo, Norway.ORCID 0000-0002-1709-6921
Christina L StallingsDepartment of Molecular Microbiology, Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, 63110 Missouri, United States.
Fredrik AlmqvistDepartment of Chemistry, Umeå University, SE-90187 Umeå, Sweden.ORCID 0000-0003-4646-0216
Umeå University · SECentre National de la Recherche Scientifique · FROslo University Hospital · NOUniversity of Oslo · NO

Funding

Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
Chemical disarming of drug resistance in Mycobacterium tuberculosisR01AI134847 · NIAID · WASHINGTON UNIVERSITY · PI ALMQVIST, FREDRIK, STALLINGS, CHRISTINA LEIGH · 2018 to 2021
$2.7M
NIAID NIH HHS R01 AI134847NIAID NIH HHS T32 AI007172
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsBacterial ProteinsDrug Resistance, BacterialHumansIsoniazidIsoxazolesMicrobial Sensitivity TestsAntitubercular AgentsBacterial ProteinsIsoniazidIsoxazoles

Identifiers

PMID37485869
PMCPMC10461229
OpenAlexW4385185976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.