Evidence map›Paper›PMID 37485581›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023

Strain hypothesis and additional evidence of the GluN3A deficiency-mediated pathogenesis of Alzheimer's disease.

Shan Ping Yu, Michael Jiang, Ken Berglund, Ling Wei

Erratum issuedOpen access · greenAbstract readLetter
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shan Ping YuDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID 0000-0003-1335-1398
Michael JiangDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Ken BerglundDepartments of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Ling WeiDepartment of Anesthesiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Emory University · US

Funding

Direct Reprogramming of the brain after ischemic stroke in the aged mouseR01NS114221 · NINDS · EMORY UNIVERSITY · PI WEI, LING, YU, SHAN P. · 2020 to 2024
$2.0M
Stem cell transplantation therapy via intranasal delivery after strokeR01NS091585 · NINDS · EMORY UNIVERSITY · PI WEI, LING · 2016 to 2020
$1.7M
Acquisition of an integrated multi-photon live imaging system for simultaneous in vitro and in vivo electrophysiologyS10OD021773 · OD · EMORY UNIVERSITY · PI BERGLUND, KEN · 2017 to 2017
$600k
The role of NMDA receptor subunit GluN3A in age and Alzheimer's disease-related dementiaR21AG067473 · NIA · EMORY UNIVERSITY · PI YU, SHAN P. · 2021 to 2022
$430k
Innovative memantine therapy for neuroprotective effects against ischemic stroke and Alzheimer's diseaseI21RX003865 · VA · VETERANS HEALTH ADMINISTRATION · PI YU, SHAN P. · 2023 to 2024
–
NIA NIH HHS R21 AG067473NIH HHS S10 OD021773NINDS NIH HHS R01 NS091585NINDS NIH HHS R01 NS114221RRD VA I21 RX003865
6 · The paper itself

Abstract

Our recent investigation revealed that deficiency of N-methyl-D-aspartate (NMDA) receptor subunit GluN3A (NR3A) is a trigger for chronic neuronal hyperactivity and disruptionFfepspof Ca

Indexed as

Alzheimer DiseaseAnimalsMiceNeuronsReceptors, N-Methyl-D-AspartateGluN3A protein, mouseReceptors, N-Methyl-D-Aspartate

Identifiers

PMID37485581
PMCPMC10528065
OpenAlexW4385150553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.