Evidence map›Paper›PMID 37485477›Full record

ArticleRheumatology and immunology research2023

Posterior reversible encephalopathy syndrome: A rare complication of rituximab therapy in rheumatoid arthritis.

Marriam Hussain Awan, Saba Samreen, Shahida Perveen, Babur Salim, Haris Gul, Anum Khan

Open access · diamondAbstract read
In one paragraph

Article in Rheumatology and immunology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. JC Polyomavirus Infection: A Narrative Review.Infectious diseases and therapy · 2025
    Review
  2. Article
  3. B-cell Depletion Therapy in Pediatric Neuroinflammatory Disease.Current neurology and neuroscience reports · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Marriam Hussain AwanDepartment of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Punjab 45000, Pakistan.ORCID https://orcid.org/0000-0002-0851-6584
Saba SamreenRheumatolgy Department, Foundation University School of Health Sciences (FUSH), Rawalpindi, Punjab 44000, Pakistan.
Shahida PerveenRheumatolgy Department, Foundation University School of Health Sciences (FUSH), Rawalpindi, Punjab 44000, Pakistan.
Babur SalimDepartment of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Punjab 45000, Pakistan.
Haris GulDepartment of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Punjab 45000, Pakistan.
Anum KhanDepartment of Rheumatology, Fauji Foundation Hospital, Rawalpindi, Punjab 45000, Pakistan.
Pakistan Army · PKFoundation University Medical College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rituximab, a murine-human chimeric monoclonal antibody targeting CD20-positive B lymphocytes, has established itself as an effective and relatively safe biologic therapy for patients with refractory rheumatoid arthritis. Most common side effects associated with its use include infusion related reactions and cytopenia. Rare adverse effects such as progressive multifocal leukoencephalopathy and posterior reversible encephalopathy syndrome (PRES) have also been reported. Diagnosis of PRES following rituximab treatment requires a high index of suspicion correlated with clinical and radiological features in individuals at risk. Early diagnosis and prompt treatment is associated with a favorable prognosis. We present a case of a young man who developed PRES following rituximab administration on account of active rheumatoid arthritis. Timely diagnosis and prompt treatment ensured his uneventful recovery without residual neurological deficit.

Indexed as

posterior reversible encephalopathy syndromerheumatoid arthritisrituximab

Identifiers

PMID37485477
PMCPMC10362588
OpenAlexW4385146101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.