ReviewEcology and evolution2023
Negative frequency dependent selection unites ecology and evolution.
Review in Ecology and evolution, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Article
- Shifting Balancing Selection Underlies an Inversion Cline in Eurasian Blackcap.Ecology and evolution · 2026Article
- Article
- Manipulating vector transmission reveals local processes inParasitology · 2026Article
- Comprehensive analysis of CBL and CIPK gene families in Magnolia biondii and functional characterization of MbCBL4 under salt stress.Plant cell reports · 2026Article
- Local negative frequency dependence can decrease global coexistence in fragmented populations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and capacity for intra-species co-operation.PLoS biology · 2025Article
- Totivirus-satellite coinfection prevalence and host genotype associations in wild Saccharomyces cerevisiae.FEMS microbiology ecology · 2025Article
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Characterisation of a persistent SARS-CoV-2 infection lasting more than 750 days in a person living with HIV: a genomic analysis.The Lancet. Microbe · 2025Article
- Linkage-based ortholog refinement in bacterial pangenomes with CLARC.Nucleic acids research · 2025Article
- The long and short of hyperdivergent regions.Trends in genetics : TIG · 2025Review
- Multiplicity of type 6 secretion system toxins limits the evolution of resistance.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Within-host competition causes pathogen molecular evolution and perpetual microbiota dysbiosis.The ISME journal · 2025Article
- Estimates of microbial community stability using relative invader growth rates are robust across levels of invader species richness.ISME communications · 2025Article
- Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life.Nature communications · 2024Article
- Tradeoffs and constraints on the evolution of tailocins.Trends in microbiology · 2024Review
- Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut.Nature microbiology · 2024Article
- The genetic basis of the kākāpō structural color polymorphism suggests balancing selection by an extinct apex predator.PLoS biology · 2024Article
- Competitive interactions affect introgression and population viability amidst maladaptive hybridization.Evolutionary applications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
From genes to communities, understanding how diversity is maintained remains a fundamental question in biology. One challenging to identify, yet potentially ubiquitous, mechanism for the maintenance of diversity is negative frequency dependent selection (NFDS), which occurs when entities (e.g., genotypes, life history strategies, species) experience a per capita reduction in fitness with increases in relative abundance. Because NFDS allows rare entities to increase in frequency while preventing abundant entities from excluding others, we posit that negative frequency dependent selection plays a central role in the maintenance of diversity. In this review, we relate NFDS to coexistence, identify mechanisms of NFDS (e.g., mutualism, predation, parasitism), review strategies for identifying NFDS, and distinguish NFDS from other mechanisms of coexistence (e.g., storage effects, fluctuating selection). We also emphasize that NFDS is a key place where ecology and evolution intersect. Specifically, there are many examples of frequency dependent processes in ecology, but fewer cases that link this process to selection. Similarly, there are many examples of selection in evolution, but fewer cases that link changes in trait values to negative frequency dependence. Bridging these two well-developed fields of ecology and evolution will allow for mechanistic insights into the maintenance of diversity at multiple levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.