Evidence map›Paper›PMID 37484872›Full record

ArticleFrontiers in reproductive health2023

Integrating PrEP in maternal and child health clinics in Kenya: analysis of a service availability and readiness assessment (SARA) survey.

Sarah Hicks, Felix Abuna, Ben Odhiambo, Julia C Dettinger, Joseph Sila, George Oketch, Enock Sifuna, Nancy Ngumbau, Laurén Gómez, Grace C John-Stewart and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in reproductive health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04712994 (PrEPARE), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04712994 nacompletednot on this map

PrEPARE: PrEP in Pregnancy, Accelerating Reach and Efficiency

TypeinterventionalSponsorUniversity of WashingtonRan2021 to 2022Enrolled1,958ConditionsPre-Exposure Prophylaxis, HIV Infections, Pregnancy RelatedArmsPrEP Optimization Interventions
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarah HicksDepartment of Epidemiology, University of Washington, Seattle, WA, United States.
Felix AbunaResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
Ben OdhiamboResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
Julia C DettingerDepartment of Global Health, University of Washington, Seattle, WA, United States.
Joseph SilaResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
George OketchResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
Enock SifunaResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
Nancy NgumbauResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
Laurén GómezDepartment of Global Health, University of Washington, Seattle, WA, United States.
Grace C John-StewartDepartment of Epidemiology, University of Washington, Seattle, WA, United States.
John KinuthiaResearch and Programs, Kenyatta National Hospital, Nairobi, Kenya.
Anjuli D WagnerDepartment of Global Health, University of Washington, Seattle, WA, United States.

Funding

University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2021 to 2024
$5.8M
Testing implementation strategies to improve delivery of PrEP for pregnant and postpartum women in KenyaK01MH121124 · NIMH · UNIVERSITY OF WASHINGTON · PI WAGNER, ANJULI DAWN · 2019 to 2023
$835k
NIMH NIH HHS K01 MH121124NIMH NIH HHS P30 MH123248
6 · The paper itself

Abstract

Background: Risk of HIV acquisition is high during pregnancy and postpartum, and pre-exposure prophylaxis (PrEP) is recommended for peripartum populations. Integrating PrEP into maternal and child health (MCH) clinics is feasible and acceptable. Understanding clinics' service availability and readiness is essential for effective scale up. Methods: The PrEP in Pregnancy, Accelerating Reach and Efficiency study (PrEPARE; NCT04712994) engaged PrEP-experienced facilities previously linked to a programmatic or research study in Western Kenya to document available services and commodities via a modified service availability and readiness assessment (SARA) survey with 20 PrEP tracer items covering: staffing/guidelines, services/equipment, and medicines/commodities. Facilities' prior study engagement occurred between 2017 and 2019; SARA survey data was collected between April 2020 and June 2021. Descriptive statistics were stratified by prior study engagement. ANOVA tests assessed associations between facility characteristics and gaps. Fisher's tests assessed differences in commodity availability and stockouts. Results: Of the 55 facilities surveyed, 60% had received PrEP training in the last two years, 95% offered PrEP integrated into MCH, and 64% and 78% had both auditory and visual privacy in PrEP and HIV testing service (HTS) delivery spaces, respectively. Supervision frequency was heterogeneous, but 82% had received a supervision visit within 3 months. Availability of commodities was variable and the most commonly unavailable commodities were PrEP in MCH (71% available) and risk assessment screening tool (RAST) and PrEP cards (60% and 75% available, respectively). The number of service and commodity gaps per facility ranged from zero to eight (median: 3; IQR: 2, 5). The most frequent gaps were: PrEP training and risk assessment cards (40% each), lack of privacy in PrEP (36%) and HIV testing services (31%) spaces, PrEP pills in MCH (29%), and PrEP cards (25%). There were no differences in mean number of gaps by county, previous study engagement, or public vs. private status. Level 4 facilities had fewer gaps (mean 2.2) than level 2, 3, and 5 facilities (mean 5.7, 4.5, and 5.3 respectively; Conclusions: PrEP service availability and readiness was generally high across MCH facilities. However, there is a need for increased frequency of provider training and supportive supervision focused on fidelity. To address key commodity stockouts such as PrEP pills, implementation of electronic logistics management information systems may be needed. Targeting these gaps is essential to effectively scale up integrated PrEP delivery, especially among facilities with limited infrastructure.

Indexed as

commoditieshealth facilities (MeSH)postpartumpre-exposure prophylaxis (PrEP)pregnancyservice readiness and availabilitysupervision

Identifiers

PMID37484872
PMCPMC10359145

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.