Evidence map›Paper›PMID 37484870›Full record

ArticleLC GC Europe2023

Exploring Biopharmaceutical Analysis with Compact Capillary Liquid Chromatography Instrumentation.

Benjamin P Libert, Samuel W Foster, Elisabeth P Gates, Matthew Morse, Greg Ward, Milton L Lee, James P Grinias

Abstract read
In one paragraph

Article in LC GC Europe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin P LibertRowan University.
Samuel W FosterRowan University.
Elisabeth P GatesAxcend LLC.
Matthew MorseAxcend LLC.
Greg WardAxcend LLC.
Milton L LeeAxcend LLC.
James P GriniasRowan University.

Funding

Portable Liquid Chromatography Platform for Diverse Pharmaceutical ApplicationsR44GM137649 · NIGMS · AXCEND, LLC · PI LEE, MILTON L. · 2020 to 2022
$1.7M
NIGMS NIH HHS R44 GM137649
6 · The paper itself

Abstract

A recent trend in the design of liquid chromatography (LC) instrumentation is the move towards miniaturized and portable systems. These smaller platforms provide wider flexibility in operation, with the opportunity for conducting analysis directly at the point of sample collection rather than transporting the sample to a centralized laboratory facility. For the manufacturing of pharmaceutical and biopharmaceutical products, these platforms can be implemented for process monitoring and product characterization directly in manufacturing environments. This article describes a portable, miniaturized LC instrument coupled to a mass spectrometer (MS) for characterization of a biopharmaceutical monoclonal antibody (mAb).

Identifiers

PMID37484870
PMCPMC10358286

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.