Evidence map›Paper›PMID 37484853›Full record

ArticleFrontiers in medicine2023

Ozone therapy as a novel complementary therapeutic approach in refractory idiopathic granulomatous mastitis.

Neslihan Cabioglu, Didem Can Trabulus, Selman Emiroglu, Enver Ozkurt, Nesli Yalcin, Nagehan Dinc, Mustafa Tukenmez, Mahmut Muslumanoglu, Abdullah Igci, Vahit Ozmen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Neslihan CabiogluIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Didem Can TrabulusDepartment of Surgery, Bahcesehir University, Istanbul, Türkiye.
Selman EmirogluIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Enver OzkurtDepartment of Surgery, Istanbul Florence Nightingale Hospital, Istanbul, Türkiye.
Nesli YalcinIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Nagehan DincIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Mustafa TukenmezIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Mahmut MuslumanogluIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Abdullah IgciDepartment of Surgery, American Hospital, Istanbul, Türkiye.
Vahit OzmenDepartment of Surgery, Istanbul Florence Nightingale Hospital, Istanbul, Türkiye.
Ahmet Sait DinccagIstanbul Faculty of Medicine, Department of Surgery, Istanbul University, Istanbul, Türkiye.
Yusuf Izzettin GuvenContinuing Medical Education, Medipol University, Istanbul, Türkiye.
Istanbul University · TRIstanbul Florence Nightingale Hospital · TRAmerikan Hastanesi · TRBahçeşehir University · TRIstanbul Medipol University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autoimmunity may play a major role in the pathogenesis of idiopathic granulomatous mastitis (IGM). The therapeutic potential of ozone therapy has recently been shown in rheumatological diseases, and this study aimed to assess the clinical efficacy of ozone therapy (OT) in refractory IGM. Methods: Patients with biopsy-verified IGM and incomplete response after steroid therapy ( Results: The median age was 33 years (range, 24-45). Patients in cohort B had a higher complete response rate after completion of a four-month ozone therapy than those in the ST-group (OT-group, 37.5% vs. ST-group, 0%; Conclusion: Systemic OT increases the complete response rate and decreases the duration of steroid treatment in patients with refractory IGM. Therefore, ozone therapy is an effective, well-tolerated, and safe novel complementary therapeutic modality.

Indexed as

idiopathic granulomatous mastitisozone therapyrefractory granulomatous mastitissteroidsteroid resistance

Identifiers

PMID37484853
PMCPMC10357005
OpenAlexW4383343748

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.