Evidence map›Paper›PMID 37484784›Full record

ArticleBiofilm2023

Kaden B Rawson, Travis Neuberger, Tyler B Smith, Isaac J Bell, Ryan E Looper, Paul R Sebahar, Travis J Haussener, Hariprasada Reddy Kanna Reddy, Brad M Isaacson, John Shero and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biofilm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kaden B RawsonDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, USA.
Travis NeubergerDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, USA.
Tyler B SmithDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, USA.
Isaac J BellDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, USA.
Ryan E LooperDepartment of Chemistry, University of Utah, Salt Lake City, UT, USA.
Paul R SebaharDepartment of Chemistry, University of Utah, Salt Lake City, UT, USA.
Travis J HaussenerDepartment of Chemistry, University of Utah, Salt Lake City, UT, USA.
Hariprasada Reddy Kanna ReddyDepartment of Chemistry, University of Utah, Salt Lake City, UT, USA.
Brad M IsaacsonBone and Biofilm Research Lab, University of Utah, Salt Lake City, UT, USA.
John SheroExtremity Trauma and Amputation Center of Excellence, Joint Base San Antonio Fort Sam Houston, San Antonio, TX, USA.
Paul F PasquinaThe Center for Rehabilitation Sciences Research, Department of Physical Medicine and Rehabilitation, Uniformed Services University, Bethesda, MD, USA.
Dustin L WilliamsDepartment of Orthopaedics, University of Utah, Salt Lake City, UT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Implementation of negative pressure wound therapy (NPWT) as a standard of care has proven efficacious in reducing both the healing time and likelihood of nosocomial infection among pressure ulcers and traumatic, combat-related injuries. However, current formulations may not target or dramatically reduce bacterial biofilm burden following therapy. The purpose of this study was to determine the antibiofilm efficacy of an open-cell polyurethane (PU) foam (V.A.C.® Granufoam™) loaded with a first-in-class compound (CZ-01179) as the active release agent integrated via lyophilized hydrogel scaffolding. An

Indexed as

A. baumanniiBiofilmMRSANegative pressure wound therapy

Identifiers

PMID37484784
PMCPMC10359492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.