ArticleFrontiers in psychiatry2023
Associations between attention-deficit/hyperactivity disorder and allergic diseases: a two-sample Mendelian randomization study.
Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Pooled it
- Comorbidity of asthma and attention deficit hyperactivity disorder in childhood: causal, shared early-life risk factors, or shared genetic liability?International journal of epidemiology · 2026Article
- Commentary: Associations between attention-deficit/hyperactivity disorder and allergic diseases: a two-sample Mendelian randomization study.Frontiers in psychiatry · 2026Article
- Allergic rhinitis and behaviour problems in urban children aged 6 to 12 years and the mediating role of sleep disturbance.Annals of medicine · 2025Article
- Parental Perspectives on Eating Disorders of Their School-Age Children with ADHD in Hong Kong: A Qualitative Study.Nutrients · 2025Article
- Allergy-unrelated eosinophil activation in the peripheral blood of children with neurodevelopmental disorders.Frontiers in neurology · 2025Article
- Unraveling the causative connection between urticaria, inflammatory cytokines, and mental disorders: Perspectives from genetic evidence.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Application of mendelian randomization in ocular diseases: a review.Human genomics · 2024Review
- Celiac disease and attention-deficit/hyperactivity disorder: a bidirectional Mendelian randomization analysis.Frontiers in psychiatry · 2024Article
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: In some observational studies, attention-deficit/hyperactivity disorder has been linked to allergic diseases, but the findings are debatable. This study aimed to determine whether attention-deficit/hyperactivity disorder (ADHD) is causally related to allergic asthma, allergic rhinitis, pollen allergy, allergic urticaria, and allergic conjunctivitis using the two-sample Mendelian Randomization (MR) approach. Methods: We did a two-sample Mendelian randomization (MR) study, which chose single nucleotide polymorphisms (SNPs) that are highly associated with attention-deficit/hyperactivity disorder (ADHD) levels from the Psychiatric Genomics Consortium (PGC) on 20,183 cases and 35,191 controls as our instruments. Outcomes datasets included genome-wide association study (GWAS) meta-analysis ( Results: The Mendelian randomization (MR) analysis indicated that ADHD in inverse variance weighted [odds ratio (OR) = 1.0612; 95% confidence interval (CI):1.0192-1.1049; Conclusion: Although several studies have found a link between ADHD and allergic diseases, our findings do not support that ADHD could increase allergic diseases incidence. Randomized controlled trials or Mendelian randomization studies with larger samples are still needed to draw more precise conclusions.
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