Evidence map›Paper›PMID 37484652›Full record

ReviewFrontiers in genome editing2023

Methods of crop improvement and applications towards fortifying food security.

Aayushi Patel, Andrew Miles, Tara Strackhouse, Logan Cook, Sining Leng, Shrina Patel, Kelsey Klinger, Sairam Rudrabhatla, Shobha D Potlakayala

Abstract readReview
In one paragraph

Review in Frontiers in genome editing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aayushi PatelPenn State Harrisburg, Middletown, PA, United States.
Andrew MilesPenn State University Park, State College, University Park, PA, United States.
Tara StrackhousePenn State Harrisburg, Middletown, PA, United States.
Logan CookPenn State Harrisburg, Middletown, PA, United States.
Sining LengShanghai United Cell Biotechnology Co Ltd, Shanghai, China.
Shrina PatelPenn State Harrisburg, Middletown, PA, United States.
Kelsey KlingerPenn State Harrisburg, Middletown, PA, United States.
Sairam RudrabhatlaPenn State Harrisburg, Middletown, PA, United States.
Shobha D PotlakayalaPenn State Harrisburg, Middletown, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agriculture has supported human life from the beginning of civilization, despite a plethora of biotic (pests, pathogens) and abiotic (drought, cold) stressors being exerted on the global food demand. In the past 50 years, the enhanced understanding of cellular and molecular mechanisms in plants has led to novel innovations in biotechnology, resulting in the introduction of desired genes/traits through plant genetic engineering. Targeted genome editing technologies such as Zinc-Finger Nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) have emerged as powerful tools for crop improvement. This new CRISPR technology is proving to be an efficient and straightforward process with low cost. It possesses applicability across most plant species, targets multiple genes, and is being used to engineer plant metabolic pathways to create resistance to pathogens and abiotic stressors. These novel genome editing (GE) technologies are poised to meet the UN's sustainable development goals of "zero hunger" and "good human health and wellbeing." These technologies could be more efficient in developing transgenic crops and aid in speeding up the regulatory approvals and risk assessments conducted by the US Departments of Agriculture (USDA), Food and Drug Administration (FDA), and Environmental Protection Agency (EPA).

Indexed as

biosecurityCRISPR/Cas9crop productionfood applicationsgene-editingplant biotechnologyplant breedingsustainability

Identifiers

PMID37484652
PMCPMC10361821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.